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Abstract:The growth and survival of Litopenaeus vannamei post larvae was measured in controlled different salinities condition 35ppt (T1), 40ppt (T2), 45ppt (T3) and 50ppt (T4) were maintained. Group of Shrimp post larvae (weight 0.032 g ± 0.002) were stocked at a density of 35 nos. /aquarium in above salinity ranges. Animals were fed with commercial feed (35% Crude Protein) @ 5% of body weight four times a day. The results indicate that higher SGR was observed in T2 (1.99±0.08) followed by T1 (1.75±0.07), T3 (1.54±0.06) and T4 (1.49±0.17). Highest survival (100 %) was recorded in T1 followed by T2 (96.42%), T3 (94.99%) and T4 (74.21%). From the results of the present study it could be seen that higher salinity significantly reduced the growth and survival of L. vannamei but will also open study area of physiological adaption of animal at higher saline water in performance of organisms.