The ICH stands for "international council on harmonization of technical requirements for registration of pharmaceutical for human use" it's an initiative which brings together regulatory bodies and pharmaceutical industry to discuss scientific and technical aspects of pharmaceutical product development and registration. ICH guidelines include 'Q' series quality guidelines for harmonization. The amendment in analytical procedure development and the changes in validation of analytical procedure ICH Q2 (R1) is proposed to develop a new quality guideline and providing principles relating to analytical development procedures. Applying this guideline will improve regulatory communication between industry and regulators and Q2(R1) will include validation principles that cover analytical use of spectrometric data (e.g, NIR, NMR, Raman OR MS).