Every three minutes, a woman in the United States is diagnosed with breast cancer. Every twelve minutes a woman dies from breast cancer. Breast cancer comprises 22.9% of all cancers (excluding non-melanoma skin cancers) in women, 1 worldwide. In 2008, breast cancer caused 458,503 deaths 1 worldwide (13.7% of cancer deaths in women). Breast cancer is more than 100 times more common in women than breast cancer in men, although males tend to have poorer outcomes 2,3 due to delays in diagnosis. No one dies of cancer in the breast, only of cancer that has spread to other parts of the body. Breast cancer is the commonest cause of cancer death in women worldwide. Rates vary about five-fold around the world, but they are increasing in regions that until recently had low rates of the disease. Lot of progress has been made in the understanding of risk factors (Table 1) and management of breast cancer. The concept of radical surgery has been replaced by the more conservative one without significant compromise in terms of results.Opting for simple mastectomy or wide local excision and adjuvant radiotherapy, rather than obligatory mastectomy, be it radical or modified radical, reflects a significant shift in the 4 understanding of breast cancer pathology and management.Multimodal treatments -both loco-regional, in the form of breast conservation surgery and radiotherapy, and systemic like endocrine treatment and chemotherapy, has resulted in reduced postsurgical morbidity without compromising 5 oncological outcomes. Neo-adjuvant chemotherapy or endocrine therapy is increasingly being applied to improve the chance of successful conservation surgery in the same way as it 6,7 can render operable the inoperable. Before discussing Breast conservative therapy, a brief mention regarding Breast cancer as such, is made below.