Antipsychotic drugs are particularly interesting in pharmacogenetic studies as they are associated with a large interindividual variability in terms of response and side effects and, therefore, frequently need to be discontinued, requiring switches to other antipsychotics. Any information that allows the prediction of outcome to a given antipsychotic in a particular patient will, therefore, be of great help for the clinician to minimize time and find the right drug for the right patient, thus optimizing response and minimizing side effects. This will also have a substantial impact on compliance and doctor-patient relationships. Moreover, antipsychotic drug treatments are often required for life-long treatment and are also frequently prescribed to the more 'vulnerable' populations: children, adolescents and the elderly. This article focuses on some important studies performed with candidate gene variants associated with antipsychotic response. In addition, important findings in pharmacogenetic studies of antipsychotic-induced side effects will be briefly summarized, such as antipsychotic treatment induced tardive dyskinesia and weight gain.

Ficus racemosa (Family: Moracae) is a prominent plant in India and it was embedded in traditional medicinal texts of India as a wound healer. Hence to study its wound healing assets, the ethanolic leaves extract was studied on animals. Excision and incision wound models were used to study wound healing activity. For both models, extract was given in the form of ointment (5% and 10 % w/w). In the excision model, all extract treated animals showed significant (P<0.01) increase in percentage wound contraction. The incision wound model showed significant (P<0.01) increase in breaking strength when compared to control. In biochemical parameter, hydroxyproline level was significantly (P<0.01) increased in all drugs treated groups as compared to control in the excision wound model. Histopathological study also showed good regeneration of skin compared to control. Phytochemical study of the leaves showed presence of flovonoids and tannins which might be the key constituents for the wound healing activity.

The present study assesses the taxonomic identity of the two recently described Indian species of Capillipedium i.e. C. mistryi and C. yashwantraoi from the state of Madhya Pradesh, central India. Both of the species share important features, such as multispiculated racemes, solid pedicel and rhachis internode (non-translucent). As these features are unique in Capillipedium they are of peculiar interest. Having multi-spiculated spiciform racemes, these taxa can be best compared with a similar, non-Indian congener, C. spicigerum which is distributed from China to Australia. Based on comparative morphological study using their protologues and the type specimens, it is concluded that C. yashwantraoi is conspecific with C. mistryi. Therefore, the former is treated as a new heterotypic synonym under the latter following the principle of priority.