Background: The goal of cleft therapy has progressed from simply correcting the deformity to uplifting the patient’s quality of life (QoL). At the end of comprehensive treatment, a patient with cleft lip and palate (CLP) should report with satisfactory QoL scores in all domains such as aesthetics, speech, function, and psychology. Objective: To develop and validate a novel, disease-specific questionnaire designed in 2 regional languages to assess the QoL in young adult patients with CLP of South India following comprehensive treatment. Methods: A preliminary questionnaire was created from the literature review and patient interviews, considering regional sociodemographic conditions. The questionnaire was then validated by subject experts and pilot tested. The resultant tool was implemented on patients at treatment completion. Data collected were assimilated for statistical evaluation. Results: The questionnaire was deemed reliable (Cronbach α = .854 and test–retest reliability, κ = 0.8) and was administered to 100 young adult patients with CLP (mean age: 22 years). A large majority (83%) of the population felt more confident about themselves, with positive responses to familial relations, social interaction, and self-image. About 25% of the patients faced problems with speech regularly, while a majority of patients did not face problems with chewing and swallowing. Nearly 60% of patients were fully satisfied with their facial appearance, while others had concerns about their lip and nose aesthetics. The results were descriptive of the local population. Conclusions: Most patients achieved satisfactory QoL in all domains following comprehensive multispeciality therapy. The novel tool is simple, reliable, and can be adapted to homogenous population groups.

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Radical surgery is the mainstay for the treatment of recurrent ameloblastomas; however, it leads to large, complex defects. In this case report, we present an innovative technique of digitally aided resection and reconstruction. A massive histologically confirmed acanthomatous ameloblastoma of the skull-base was digitally mapped with the help of three-dimensional (3D) computed tomography and a custom resection template was fabricated. Digital resection of the skull-base tumor with intracranial extension was done virtually and the resultant defect was reconstructed to create an anatomical replica of the contralateral unaffected side. The tumor was successfully resected with adequate margins guided by the resection template to avoid injury to adjacent vital structures. Subsequent reconstruction was performed by first adapting polymethyl methacrylate bone cement into a series of custom-made 3D molds. Once set, this bone cement served as a reconstructive implant to bridge the ablative defect. The implant offered a precise fit and was secured to healthy adjacent bone using titanium microplates. We present a 6-month follow-up of the case with satisfactory aesthetic results. 3D printing technology has the potential to revolutionize the arena of craniofacial resection with excellent cosmesis and no donor site morbidity if applied appropriately as described here.

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