This paper seeks to determine the optimum operating conditions for deploying casing perforation guns based on CT to target depths in gas well MA-X by utilising Orpheus Model in CERBERUS. Orpheus assisted to solve the complicated scenarios and complex analysis involves mathematical modelling which is necessitates for computer processing powers. This study investigated four different Coiled Tubing (CT) intervention operational variables namely borehole assembly, CT grade outer diameter (OD), well fluid type and fractional reducer application included examined two scenarios which are running tools in (RIH) and pulling out from borehole (POOH). Only CT workstring with outer diameter between 1-1/4 inch and 2-7/8 inch is considered due to the wellbore completion minimum restriction. Constrained by economic and logistical reasons, only fresh water, 2% KCl, 15% HCl, sea water and diesel will be considered for the well bore fluid. Fractional reducer effects was simulated and analysed. Based on simulation results, the CT outer diameter 1-3/4 inch workstring optimized operation, the CT grade is QT1000 increased mechanical properties. A suitable well fluid is sea water with application of friction reducer improve CT perforation performances to achieve maximum target depth.