In the medical era the Brain tumor is one of the most important research areas in the field of medical sciences. Researcher are trying to find the reliable and cost effective medical equipment’s for the cancer and its type for the diagnosed, especially tumor has deferent kinds but the major two type are discussed in this research paper. Which are the benign and Pre-Malignant, this research work is proposed for these factors such as the accuracy of the MRI image for the tumor identification and actual placing were taken into consideration. In this study, an algorithm is proposed to detect the brain tumor from magnetic resonance image (MRI) data simple. As enhance the image quality for the easiness the tumor treatments and diagnosed for the patients. The proposed algorithm enhances the MR image quality and detects the Brain tumor which helps the Physician to diagnose the tumor easily. As well this algorithm automatically calculates the area of tumor, size and location of the tumor where it is present for diagnostic the Patient.

Aim: To determine the calcium and bone disorders in pregnancy assessed through radiological imaging. Study design: Prospective study. Place and duration of study: Department of Radiology, Chandka Medical College Hospital, Larkana from 1st July 2022 to 31st December 2022 Methodology: One hundred pregnant women were enrolled. The blood calcium levels were assessed through serum calcium at these stages through 3 cc blood withdrawal. Dietary intake of calcium was also assessed through food frequency charts. Urinary-excretion of calcium was analyzed through cross-linked N-telopeptides (NTx) type I collagen. Each participant was assessed at 3 points including baseline assessment at 1st trimester, then at 2nd trimester and finally at post-partum 4 weeks. At the 2nd trimester ultrasound bone measurement was conducted at distal radius. Quantitative ultrasound was used for this purpose. In the post-partum women, a radiological imaging including DEXA (Dual-energy X-ray absorptiometry) bone scan was performed. Results: The mean age was 26.9±5.5 years. The mean pregnancy was 2.0±1.1 while the mean number of children was 0.9±0.7. The previous months of breast feeding as mean were 6.8±7.9. The calcium intake from food as well as serum calcium levels was below recommended levels in women during their pregnancy and post-delivery. Through the quantitative ultasound and bone density DEXA scan images presented obvious osteoporotic changes in bone density. There were 24% had 2.5 or less meant osteoporosis formation. Conclusion: Women often lead to calcium deficiency during gestation and lactation and thus chances of musculoskeletal disorders escalate manifolds. Radiological imaging can facilitate in detecting these calcium deficiencies. Keywords: Hemostasis, Regulation, Pregnancy, Mineral absorption

Aim: To identify the incidence of spina bifida during gestation and its pregnancy outcomes. Study design: Cohort study Place and duration of study: Department of Radiology, Chandka Medical College Hospital, Larkana from 1st October 2020 to 30th September 2022 Methodology: One thousand pregnant women who were screened for the identification of spina bifida. Doppler based ultrasonography was performed in each patient. The fetus body was examined during sonography Doppler between 18-24 weeks. The body of the fetus was focused and visualized longitudinally in midsagittal section. Spinal cord was traced from neck to sacral, cervical vertebra and thorax. A tram track appearance was observed. Spinal nerve positioning was also observed. In spina bifida nerve tethering was seen. The primary outcomes in reference to baby weight and maturity were recorded while secondary outcomes of the fetuses in terms of any disability were followed up to 12 months of age. Results: The mean age of the women was 25.6±5.6 years. The incidence of spina bifida was 1.1%. Within the primary outcomes observed birth weight ranged within 3.1-3.5kg. Around 81.81% cases were born full term while 18.18 were premature. On 06 months’ follow-up of the spina bifida cases it was observed that 45.45% of new born suffered from skin problems as sores, calluses or and blisters while 36.36% had hydrocephalus with excessive CSF which needed monitoring. Mobility issue and disability was observed in 27.27% cases. Conclusion: Spina bifida cases are identified successfully within gestational period. Prematurity can be significantly noticed in spina bifida cases. The lumbosacral and lumbar lesions are most common as well as skin conditions and hydrocephalus. Key words: Incidence, Spina bifida, Gestation, Outcome

Aim: To assess the role of computed tomography for management of Covid-19. Study design: Prospective study Place and duration of study: Department of Radiology, Ghulam Muhammad Mahar Medical College Teaching Hospital Sukkur from 1st November 2020 to 31st December 2021. Methodology: One hundred cases within various ages 5-55 years for analyzing their risk for CT scanning on them by highlighting the facts related to CT scan, patient perceptions and uncertainties regarding it. A 50 radiologist and 50 emergency doctors were also asked questions regarding their knowledge about CT scan risks and their responses were also documented. However previous CT record of patients suffering from carcinoma was also analyzed for understanding the fact related with CT imaging. Results: The mean age of patients undergoing CT scan was 39.5±5.6 years. There were 55% males who underwent CT scans while 45% females. The usual dosage for various radiological procedure shows that highest dose deliverance was given to the patients of CT pulmonary angiogram and coronary angiography. Only 50% of radiologists knew that CT scan is associated with high risk of malignancies. There were only 10% emergency medical doctors who also knew CT imaging relation with malignancy risk. Only 54% patients considered abdomen pelvic scan to be associated with increasing lifetime risk of cancer while 23% of the patients considered chest scan to be associated with escalating the risk of cancer. Conclusion: Computed tomography scan is related with a high risk of radiation exposure. There is a dire need of perception development and risk understanding with medical professionals and general public for minimizing this risk. Key words: Computed tomography, Risk, Facts, Perception, Uncertainties

Aim: To assess the role of chest computed tomography for management of Covid-19. Study design: Prospective study Place and duration of study: Department of Radiology, Peoples University of Medical & Health Sciences for Women, Nawabshah, Shaheed Benazirabad from 1st August 2020 to 30th September 2021. Methodology: Two hundred patients were enrolled within the age range of 18-70 years. The clinical/medical record of all those patients who were moderately to critically ill assessed in detail. These patients visited the hospital with symptoms of cough, fever, hypoxia, dyspnea, diarrhoea, flu, headache and other related symptoms. All patients underwent chest reverse transcription polymerase chain reaction as well as chest computed tomography scan. The reverse transcription polymerase chain reaction was performed through nasopharyngeal swab. Results: The mean age of the patients was 64.5±5.6 years with 120 (60%) males and 80 (40%) females. The specificity was 75%, sensitivity 100%, positive predictive value 79%, negative predictive value 66.67% and diagnostic accuracy 75%. Conclusion: Computed tomography scan imaging is a most reliable with high sensitivity and non-predictive value Key words: Role, Computed tomography imaging, Management, Covid-19