Background: Adenomyosis is characterized by the detection of endometrial glands and stroma within the myometrium about one and a half low power field away from endomyometrial junction. There are also smooth muscle changes associated with the main findings ,although they are less obvious and difficult to quantify on routine histological examination Materials and Methods: Case records of the patients who had undergone hysterectomy in Govt. Medical College Jammu from January 2017 to December 2018 were reviewed and number of cases diagnosed as Adenomyosis were recorded. Out of 1356 patients who underwent hysterectomy, 176 patients were found to have Adenomyosis. Majority were between age group of 31 to 50 years. Results: Adenomyosis was present in 176 patients out of 1356 hysterectomies during a study period of 2 years. The comorbid conditions were seen in 80 patients. Majority of age group was between 31 to 50 years. Comorbid conditions included • Menorrhagia • Dysmenorrhea • Intermenstual pelvic pain • Post menopausal bleeding • Dyspareunia.
BACKGROUND Anaemia is a global public health problem affecting both developing and developed countries. The morphological typing of anaemia is essential in clinical haematology for diagnostic and treatment purposes. Over the past few years, complete blood count (CBC) by automated haematology analysers and microscopic examination of peripheral smear have complemented each other to provide a comprehensive report on patient's blood sample. Despite this wealth of information, there are still morphological abnormalities that are critical in the differential diagnosis of anaemia and that can be determined only from a blood smear. The present study aims to evaluate the utility of peripheral blood smear examination in presence of automated haematology analyser with reference to anaemia after correlating type of anaemia based on RBC indices obtained from automated haematology analyser and on peripheral blood smear examination. METHODS This is a cross-sectional study conducted for a period of one year from November 1, 2017 to October 31, 2018 on 100 anaemic patients of Government Medical College, Jammu and Associated Hospitals. EDTA anticoagulated samples were received in the laboratory and run on automated haematology analyser to obtain complete blood count including RBC indices. Simultaneously, well prepared and tongue shaped peripheral blood smears stained by Leishman's stain were studied in detail to observe the morphology of red blood cells. RESULTS On classifying anaemias into five major groups, it was seen that there were 40 patients of normocytic normochromic anaemia with normal RDW which correlated well with 40 patients of normocytic normochromic anaemia on peripheral blood film examination. Normocytic hypochromic anaemia with normal RDW was seen in 5 patients, whereas PBF showed normocytic hypochromic anaemia in 7 patients. 31 patients had microcytic hypochromic anaemia (with normal and raised RDW) as per analyser generated indices which correlated well with 29 patients of microcytic hypochromic anaemia on PBF. Both analyser and PBF showed that 10% patients had macrocytic anaemia. Dimorphic anaemia was seen in 14% patients on PBF. Out of 100 cases, 84% (84) of the cases showed concordance in the type of anaemia by analyser generated RBC indices and on peripheral blood film examination. Only 16% cases showed discordance in the type of anaemia which needed peripheral blood film examination for correct morphological classification of anaemia. CONCLUSIONS RBC parameters on analyser along with PBF findings are complimentary to each other rather than being the substitute. PBF is very important in certain clinical settings in patients with normocytic normochromic anaemia with raised RDW, pancytopenia and patients of fever who show normal or slightly abnormal parameters on analyser. Each haematology report has to be interpreted along with clinical presentation of the patient in order to arrive at diagnosis.
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