Abstract:This study examined 1631 college students' endorsement of traditional Confucian values in four East Asian cultural contexts (i.e., China, Korea, Japan and Taiwan). Findings showed that young people endorsed values of interpersonal harmony the most, followed by the relational hierarchy and traditional conservatism respectively. Results also indicated that participants in China provided the highest ratings for interpersonal harmony and relational hierarchy among the four cultures. Finally, results demonstrated that Japanese females were more conservative than Japanese males and females in China and Taiwan. Results were discussed in the philosophical tradition of Confucianism, globalization and culture change in the East Asian cultures. Text of paper:Harmony Zhang, Y. B., Lin, M.-C., . Harmony, Hierarchy and Conservatism: A Cross-Cultural Comparison of Confucian Values in China, Korea, Japan, and Taiwan. Communication Research Report, 22,[107][108][109][110][111][112][113][114][115] http://dx.doi.org/10.1080/00036810500130539, Open Access version: http://kuscholarworks.ku.edu/dspace/. The major interest of cross-cultural studies tends to focus on how cultures differed in the outcome variable (e.g., conflict management style) than in the input variable (i.e., cultural values).Cultural values are frequently treated as a post-hoc explanation to offer validation of the significant results on how cultures differed in the outcome variable (e.g., Lee & Rogan, 1991). While lumping countries together based on their geographical and/or cultural proximity is still a common approach in cross-cultural research (Cross, 1995), Bond (1996) 4 harmonious relationships with others, which are the precondition of social integration and stability, individuals should respect and follow tradition and social hierarchy (rules, status, and authorities) (Chinese Cultural Connection, 1987). These values reflect the core principles of Confucianism, which has influenced Chinese people's attitude toward life and served as standards and rules for social interaction (Bond, 1996).In the process of civilization, Confucianism has spread its influence to neighboring countries of Mainland China (e.g., Korea, Japan) for thousands of years (Chang, 1997). Deliberate effort to promote and maintain Confucianism is evident in these societies. Confucian principles are permeated in media, taught in schools, and praised by officials (Tu, 1996 5Asian societies or "mini-dragons" (e.g., Taiwan, Japan and Korea; Tu, 1996), hence has maintained more of its indigenous cultural values. Therefore, we proposed our second hypothesis:H2: Chinese young participants will endorse the Confucian values more than their counterparts in Japan, Korea and Taiwan.Confucianism emphasizes that things and persons should fall into proper places and order, so that they can relate to each other in a supportive and harmonious manner. One of the traditional social orders in relationships that Confucius specified is gender role with men having more status than women (Pek & Leong, ...

To determine whether there are abnormalities in myocyte excitation-contraction coupling and intracellular Ca2+concentration ([Ca2+]i) homeostasis in pacing-induced heart failure (PF), we measured L-type Ca2+ current ( I Ca,L) and Na+/Ca2+exchanger current ( I Na/Ca) with voltage clamp and measured intracellular Na+ concentration ([Na+]i) and [Ca2+]iwith the use of sodium-binding benzofuran isophthalate (SBFI) and fluo 3 in ventricular myocytes isolated from control and paced rabbits. The peak systolic and diastolic levels and the amplitude of electrically stimulated [Ca2+]itransients (0.25 Hz, extracellular Ca2+ concentration = 1.08 mM) were significantly less in PF myocytes. Also, there was prolongation of the times to peak and decline of [Ca2+]itransients. I Ca,Ldensity was markedly decreased in PF myocytes. I Na/Ca at −40 mV elicited by rapid exposure to 0 Na+ solution with a rapid solution switcher was significantly reduced in PF myocytes, suggesting that the function of the Na+/Ca2+exchanger is impaired in these myocytes. In PF myocytes the decline of the [Ca2+]itransient when the Na+/Ca2+exchanger was abruptly disabled was markedly prolonged compared with the decline in control myocytes, consistent with depressed sarcoplasmic reticulum (SR) Ca2+-ATPase function. RNase protection assay showed decreased levels of Na+/Ca2+exchanger and SR Ca2+-ATPase mRNA in PF hearts, consistent with the function studies. We conclude that the functions of L-type Ca2+channels, Na+/Ca2+exchanger, and SR Ca2+-ATPase are impaired in myocytes from rabbit hearts with failure induced by rapid pacing. These abnormalities result in reduced [Ca2+]itransients and systolic and diastolic dysfunction and appear to account for the abnormal ventricular function observed.

We examined the dependence of peak Na+ pump and Na+/Ca2+exchanger currents on prior Na+pump inhibition induced by exposure to zero extracellular K+ in voltage-clamped adult murine ventricular myocytes. Abrupt activation of the Na+ pump by reexposure of myocytes to extracellular K+ with a rapid solution switcher resulted in the development of a transient peak current at ∼500 ms, followed by a decline over 1–2 min to a steady-state level. The magnitudes of both the peak Na+ pump current ( I p) and the peak outward Na+/Ca2+exchange current, activated by rapidly reducing extracellular Na+ to zero with the solution switcher, were dependent on previous Na+ pump activity. [Na+] gradients (Na+-binding benzofuran isophthalate fluorescence) between the patch pipette and the bulk cytosol were relatively small and could not account for the large differences between peak and steady-state I p and reverse Na+/Ca2+exchanger currents. Our results are consistent with the presence of a subsarcolemmal Na+ concentration gradient, which is similar for the Na+ pump and the Na+/Ca2+exchanger. These findings also support the hypothesis that the Na+ pump and the Na+/Ca2+exchanger are colocalized in the sarcolemma.

Abstract] i transients in nifedipine in TG myocytes was much slower than when both the L-type Ca 2ϩ current and the Na ϩ -Ca 2ϩ exchange current function together. In TG myocytes, action potential amplitude and action potential duration at 50% repolarization were reduced, and action potential duration at 90% repolarization was increased, relative to WT myocytes. These data suggest that under these conditions, overexpression of the Na

There are only limited data on sevoflurane minimum alveolar concentration (MAC) in rats. This study was designed to determine the minimum alveolar concentration value for sevoflurane in younger and older rats. Minimum alveolar concentration determination was performed in spontaneously breathing animals, 9-week-old rats (younger, n = 8) and more than 13-month-old rats (older, n = 8). Rats were instrumented with a silastic catheter in the abdominal aorta via the femoral artery to allow for arterial blood gas sampling. Subsequently, minimum alveolar concentration for sevoflurane was determined in 40 younger and 38 older rats. Minimum alveolar concentration for sevoflurane in younger rats was significantly higher than in the older rats (2.68 +/- 0.19 vs. 2.29 +/- 0.19, P < 0.001). Subgroup analysis indicated that minimum alveolar concentration for sevoflurane was not affected by the presence of an arterial catheter in the abdominal aorta (younger, 2.75 +/- 0.08 vs. 2.67 +/- 0.21; older, 2.23 +/- 0.19 vs. 2.30 +/- 0.18). Minimum alveolar concentration is profoundly affected by the age of the animal, but not by limited instrumentation.