Objectives. Peripheral artery disease (PAD) is a significant prognostic marker of poor long-term survival due to limited physical activity associated with various functional problems, such as intermittent claudication. A physically active lifestyle has the potential to modify peripheral artery risk factors and promote general health. While low daily physical activity levels have been recognized in the population of PAD, the exact level has yet to be quantified due to lack of research. The aim of the present study was to compare physical activity level (PAL) and time spent at activities of different intensity levels between patients with PAD and healthy individuals. The study subjects were 10 patients with PAD and 10 age-matched healthy control subjects. We measured the time spent at light, moderate, or vigorous physical activity using triaxial accelerometer and calculated PAL. Intermittent claudication onset distance and maximum walking distance were defined as the distance walked at which the subject first reported leg pain and the distance at which the subject was unable to continue walking because of leg pain, respectively. Results. Our results showed (i) lower PAL in patients with PAD compared with the controls; (ii) while there was no significant difference in the high-intensity activity between the two groups, the light- and moderate-intensity activities of the PAD group were significantly lower than the controls, the time spent at moderate-intensity activity was approximately 50% less; and (iii) among patients with PAD, low PAL did not correlate directly with intermittent claudication. Conclusions. PAD patients limit the amount of their physical activity, especially light and moderate intensities. Our study highlights the importance of spending more time walking in daily life.

The obesity rate in both males and females has been lower in Japan than in other countries. However, the prevalence of metabolic syndrome-related risk factors is not low when compared with that in Western countries. In this study, we aimed to evaluate the health state of young, non-obese adults in Japan. [Participants and Methods] We recruited 20 young, non-obese Japanese male university students and examined the maximum oxygen consumption, physical activity, and components of metabolic syndrome. We evaluated the physical activity level and dietary habits of the participants through a questionnaire survey. [Results] The questionnaire survey revealed that 70% participants had non-standard dietary habits, 55% did not engage in any regular exercise, and 25% were inactive. On examination, 20% participants had at least one positive risk factor for metabolic syndrome. The homeostatic model assessment of insulin resistance and triglyceride values did not correlate with the body mass index of the participants; however, the values were inversely related to the maximum oxygen consumption levels. [Conclusion] Even participants with normal body mass index had poor dietary habits and a lack of exercise. Our results confirmed that even non-obese Japanese individuals have certain health risks and that having higher maximum oxygen consumption has beneficial effects in preventing the risk factors of severe and life-threatening diseases.

In three cases of primary pulmonary amyloidosis the chief complaint was hemosputum. The diagnosis of amyloidosis was made using histochemical analysis of bronchial wall biopsy in all cases; multiple nodular lesions were observed in trachea and bronchi on flexible fiberoptic bronchoscopy. The surface of the tracheobronchial mucosawas smooth but bled easily. In oiie patient, chest X-ray film showed a solitary nodular shadow in the left lower lung field. These three cases were tracheobronchial amyloidosis, and one case was combined with nodular parenchymal type amyloidosis. (Internal Medicine 37: 687-690, 1998)