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These results provide the first evidence that coronary spasm is associated with inflammation of coronary adventitia and PVAT, where F-FDG PET/CT could be useful for disease activity assessment. (Morphological and Functional Change of Coronary Perivascular Adipose Tissue in Vasospastic Angina [ADIPO-VSA Trial]; UMIN000016675).

We propose and demonstrate a pulse compression technique using a hollow fiber with a pressure gradient. This technique improves the spatial and spectral qualities of femtosecond laser pulses spectrally broadened by self-phase modulation, and allows an increase of the pulse energy for pulse compression. Using chirped mirrors for dispersion compensation, we have successfully compressed the pulse to less than 10 fs with an energy as high as 5 mJ.

We demonstrate methods to increase the energy incident on hollow fibers for spectral broadening by self-phase modulation. We used chirped pulses for spectral broadening, lowering the optical intensity to avoid ionization of the gaseous medium. We also used helium as a nonlinear medium and demonstrated the generation of 5.0fs, 5.0mJ pulses at a repetition rate of 1kHz using a pressure gradient hollow-fiber pulse compressor.

No abstract