The nasal mucociliary system is significantly deteriorated in severe OSAS patients and they should be meticulously observed to prevent sinonasal infections. Measures to enhance mucociliary activity in these patients should be taken. Smoking, a well-known inhibitor of mucociliary activity, also has a negative impact on the mucociliary function of OSAS patients and quitting smoking would be of benefit for these patients.
Background Establishing a relationship between COVID-19 severity and olfactory dysfunction may be beneficial in-patient follow-up. Thus, in this study, we aimed to evaluate the association between self-reported olfactory dysfunction and the clinical stages of COVID-19. Material and Methods The patients included in this study were divided into three groups according to the severity of the novel coronavirus disease as mild, severe, and critical (life-threatening) patients. Patients were then contacted by phone and asked questions with the help of structured documentation form that evaluated their general status, sense of smell, taste and compared the data within the three groups. Results Among the 126 subjects evaluated in the present study (mild, n=51; severe, n=53, critical, n=22), 61 of the participants were males, and 65 were females. The findings showed that olfactory loss was the most prominent feature of the COVID-19's mild clinical course and the majority of the patients with loss of smell were female and young patients. Conclusions The findings obtained from clinically mild cases suggest that more olfactory dysfunction, indicating that the effects of viral load alone, is not decisive for olfactory dysfunction.
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