Given the most frequent manifestation of psoriasis at a young working age and in some cases severe, continuously recurrent course, the presence of many treatments, none of which is a guarantee of complete recovery and no recurrence – now there is an urgent need to find prognostic signs therapy and prevention of relapses. In the absence of ideal biomarkers, the study of constitutional markers becomes crucial. The aim of the study was to examine the differences in girth body sizes between healthy and/or psoriatic men depending on the severity of the disease. Anthropometric examination according to V.V. Bunak was performed for 32 men of the first mature age patients with mild and 68 with severe psoriasis course. The PASI index was used to clinically assess the severity and area of psoriatic lesions. The control group, according to anthropometric parameters, consisted of 82 practically healthy men of the same age, selected from the database of the research center of National Pirogov Memorial Medical University, Vinnytsya. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. In patients with psoriasis of mild and severe course, compared with healthy, we found: greater values for – the girth of the shoulder in a tense state by 8.9% and 6.8%; shoulder girth in the unstressed state by 14.2% and 12.3%; forearm girth in the upper part by 8.0% and 7.1%; forearm girth in the lower part by 4.2% and 4.5%; hand girth by 5.1% and 5.8%; hip girth by 11.4% and 9.3%; hips circumference by 8.7% and 6.5%; crus girth in the upper part by 10.2% and 7.9%; crus girth in the lower part by 8.7% and 5.9%; neck girth by 6.9% and 7.8%; waist circumference by 17.1% and 18.2%; chest girth on inspiration by 7.8% and 7.2%; chest girth on exhalation by 10.6% and 10.3%; chest circumference at rest by 10.0% and 9.6%. Thus, there are pronounced differences in the girth sizes between healthy and patients with mild and severe psoriasis Ukrainian men of the first mature age. Between patients with varying degrees of severity of dermatosis, differences are established only for the girth of the crus in the lower part.

Annotation. One of the most important problems of modern dermatology is the individualization of programs for diagnosis, treatment and prevention of skin diseases. The success of its solution largely depends on how fully, systematically will be described and somatic and mental components of the patient’s personality, taking into account the full range of biological and mental factors that affect his health. The aim of the study was to establish the features of the leading typological characteristics of temperament and psychodynamic personality traits between healthy and psoriatic men without taking into account somatotype and representatives of mesomorphic and endo-mesomorphic somatotypes. Men aged 22 to 35 years, patients with psoriasis (n=100, including 32 with mild and 68 with severe) conducted an anthropometric examination according to V. V. Bunak Somatotype was calculated according to the mathematical scheme of J. Carter and B. Heath. The PASI (Psoriasis Area and Severity Index) was used to clinically assess the severity and area of psoriatic lesions. The control group consisted of anthropometric data of 82 practically healthy men of the same age group from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya. Evaluation of the leading typological characteristics of temperament was determined by G. Eysenck, psychodynamic personality traits – by C. D. Spielberger in the modification of Y. L. Khanin Statistical processing was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. When comparing the studied indicators between groups with different disease course, significantly higher and tendencies to higher values of the percentage were found: persons with potential introversion among patients in general (19.12 %) and endo-mesomorphs (22.22 %) with severe course compared to healthy subjects without taking into account the somatotype (8.54 %) and the control group of a similar somatotype (0 %); persons with a low level of neuroticism among patients in general (50.00 %), mesomorphs (46.43 %) and endo-mesomorphs (75.00 %) with mild psoriasis compared with patients without somatotype, mesomorphs and endo-mesomorphs with severe dermatosis (19.12 %., 18.18 % and 11.11 %); persons with an average level of neuroticism among patients in general (22.06 %) and mesomorphs (20.00 %) with severe psoriasis compared with patients without somatotype and mesomorphs with mild dermatosis (3.13 %, 3.57 %); persons who answered insincerely, among patients with mild psoriasis (87.50 %) compared with patients with severe psoriasis (66.18 %); persons with a low level of situational anxiety among patients in general (12.50 %) and mesomorphs (14.29 %) with a mild course of psoriasis compared with patients without somatotype and mesomorphs with a severe course of dermatosis (2.94 % and 3.04 %); persons with a low level of situational anxiety among patients in general (21.88 %) and mesomorphs (17.86 %) with a mild course of psoriasis compared with patients without somatotype and mesomorphs with a severe course of dermatosis (8.82 % and 5.45 %). When comparing the studied indicators between groups with different body type, significantly higher and tendencies to higher values of the percentage of people with an average level of situational anxiety among endo-mesomorphs with mild and severe psoriasis (100 % in both cases) compared with mesomorphs. the corresponding severity of the disease (63.64 % and 46.43 %); persons with a high level of situational anxiety among mesomorphs with severe psoriasis (30.91 %), compared with endo-mesomorphs with a corresponding severity of the disease (0 %); persons with a low level of personal anxiety among endo-mesomorphs suffering from severe psoriasis (22.22 %), compared with mesomorphs suffering from dermatosis of similar severity (5.45 %); persons with a low level of personal anxiety among healthy endo-mesomorphs (46.15 %) compared with healthy mesomorphs (12.82 %); persons with an average level of personal anxiety among healthy mesomorphs (71.79 %) compared with healthy endo-mesomorphs (30.47 %). Thus, our study, conducted using a constitutional approach, allowed us to describe systemic portraits of patients with psoriasis, including the strengths and weaknesses of their morphological and mental organization, necessary to justify differentiated approaches to planning health and prevention measures.

Using a constitutional approach to predict the onset of a disease can be key not only to solving the problem of late-stage lifestyle modification therapy but also to understanding the deep, seemingly incomprehensible links between organs and body structure. The aim of the study was to establish and analyze the differences in total, longitudinal and transverse body sizes between healthy and/or psoriatic men of different somatotypes depending on the severity of the disease. Anthropo-somatotypological examination was performed on Ukrainian men (aged 22 to 35 years) with psoriasis (n=100, including 32 with mild and 68 with severe). A clinical assessment of the severity and area of psoriatic lesions was performed using the PASI index. Anthropometric data of 82 practically healthy men of the same age group was taken from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of the obtained results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. In patients with mild and severe psoriasis, men of mesomorphic and endo-mesomorphic somatotypes in comparison with healthy men of the corresponding somatotypes, higher values of almost all total (in the endo-mesomorphs with severe disease), transverse (except for shoulder width) and lateral body size (except endo-mesomorphs with severe disease) was found. In patients with psoriasis, men of endo-mesomorphic somatotype with a mild course of the disease found greater than in patients with a similar course men of mesomorphic somatotype, body weight, length and surface area, height of acromial and finger anthropometric points, and transverse middle thoracic diameters and anteroposterior middle thoracic diameter; and in patients with psoriasis men of endo-mesomorphic somatotype with a severe course of the disease – only greater values than in patients with a similar course of the disease men of mesomorphic somatotype, interspinous distance. When comparing the total, longitudinal and transverse dimensions of the body between men with psoriasis of the corresponding somatotypes, in representatives of the mesomorphic somatotype with a mild course of the disease found greater than with severe course, body length values and lower – posterior middle thoracic diameter. The revealed differences in total, longitudinal and transverse body sizes between healthy and/or patients with mild or severe psoriasis Ukrainian men of mesomorphic and endo-mesomorphic somatotypes provide an opportunity to increase the effectiveness of the use of body structure and size to identify risk groups psoriasis.

Significant prevalence and multifactorial occurrence of psoriasis are the main reasons why this disease has been studied for years by scientists in the field of dermatology. Finding tools to predict the occurrence and severity of this disease is one of the key unrealized areas of modern medicine in the field of skin diseases. The purpose of the study is to build and analyze discriminant models of the possibility and features of psoriasis course in Ukrainian men without and taking into account the somatotype, depending on the structure and size of the body. Anthropometric and somatotypological examination of 82 practically healthy and 100 patients with mild and severe psoriasis was performed. Construction of discriminant models of the possibility of occurrence and features of psoriasis depending on anthropo-somatotypological indicators is performed in the license package “Statistica 5.5”. It was found that men of the general group and representatives of the mesomorphic somatotype can reliably interpret the obtained classification indicators both between healthy and patients with psoriasis of different course, and between men with psoriasis of mild and severe course (correctness 84.1% of cases, statistics Wilks’ Lambda=0.074, р<0.001 in the general group, correctness 83.6% of cases, statistics Wilks’ Lambda=0.077, р<0.001 in mesomorphic somatotype). In men of endo-mesomorphic somatotype, a reliable interpretation of the obtained classification indicators is possible only between healthy and psoriatic men (correctness 84.6%, statistics Wilks’ Lambda=0.027, р<0.001). Discriminant models in men of the general group include body diameters and SFT (44.4% each) and the fat component of body weight (11.1% each); in men of mesomorphic somatotype – body diameters (57.1%), SFT (28.6%) and body surface area (14.3%); in men of endo-mesomorphic somatotype – body diameters (60.0%) and SFT on the thigh and the height of the finger anthropometric point (20.0% each). The greatest contribution to discrimination in men of the general group and representatives of the mesomorphic somatotype is made by shoulder width, and in men of endo-mesomorphic somatotype – shoulder width, interspinous and intercristal distances. The results obtained, especially in the division of men into somatotypes, indicate a high genetic predisposition to psoriasis.