No abstract

Various conditions may mimic osteosarcoma. The differential diagnosis of osteosarcoma is broad. A proper history, examination, diagnostic imaging studies, and pathological analysis are essential to establish the precise diagnosis. This case report serves to illustrate the significance of recognizing similarities and other rare features to prevent late or misdiagnosis.

Background: Increasing use of oral cytotoxic chemotherapy among cancer patient in Sudan, rising important concern about safety practicing and using of these drugs. This study aimed to assess and demonstrate patient awareness regarding their oral cytotoxic drugs regimen in Radiation and Isotopes Center at Khartoum (RICK), as it considered one of the essential hospital cancer treatments in Sudan. Method: Across-sectional study was carried out at (RICK) hospital outpatient pharmacies. Data were collected by interviewing 100 patients and answering question about their drug regimen, side effects & management, handling & storage and drug/food/herb interactions. Result: The study showed that 46% of participants have missing knowledge about their drug using and taking. Complaints reported by patients, when using their drugs, vary. Myelosuppression is the most common (40.2%). In side effect management, the study showed that 26% of the patients are referred to the community pharmacy and 67% are using medication without a prescription. Regarding the awareness of using herbal treatments, 42% of patients are using or have used herbs with their drugs. 69% of patients using herbs said that they do not inform the caregiver. For the proper drug handling and storage in the home setting, 59.6% of patients said they did not receive instructions about handling and storage. The degree of patient knowledge about the proper handling and storage are variable. Finally, patient's knowledge about their drug regimen was significantly associated with drug education, an age of 13-45 years and regularity of clinic visits (p =0.018). Conclusion: The study concluded that awareness of patients is very low regarding the toxicity of these drugs and education of patients for oral cytotoxic chemotherapy vary substantially. The development of therapeutic educational programs is essential to ensure safe practice when using oral cytotoxic drugs.

Background: Increasing use of oral cytotoxic chemotherapy among cancer patient in Sudan, rising important concern about safety practicing and using of these drugs. This study aimed to assess and demonstrate pharmacist dispensing pattern and their educational role toward patients on oral cytotoxic drugs regimen in Radiation and Isotopes Center at Khartoum (RICK). Methods: Across-sectional study was carried out at (RICK) hospital pharmacies. Data collected by using self-administered questionnaire distributed to all staff in active works (40 pharmacists) during February 2016. Results: All the participants responded to the questionnaire. The study reported variation among pharmacists when checking prescription. In which 97.4% of them checked drug name while only 76.9% calculating the dose according to the body surface area. For the patients-pharmacist counseling and it is effectiveness the study revealed that 77.5% of pharmacist providing counseling for the patient at the first visit. 75% of pharmacists counseling the drugs regimen. 28.1% of them including the drugs side effects and management. The counseling of the drugs handling and storage was registered by 65.6% of the participants. 53.1% of the pharmacists advice the patients to swallow the tablets and not crush it. The drugs interaction was counseled by 9.4% and only 2% of pharmacists counseled patients about medications teratogenicity. The finding revealed significant association between pharmacist experience and counseling practice by chi-square (p-value=0.008) while, the hospital training and staff attending has on significant association with (p-value=0.922, p-value=0.479). Conclusion: The study concluded that dispensing practice among pharmacists was main divers. Moreover, most of the pharmacists followed no standard when counseling patients and their experience becomes the main source when educating them.