The haematology and growth study of albino rats fed varying inclusions of cooked canavalia plagiosperma piper seed meal based diets was studied. Raw seeds of Canavalia plagiosperma (Oblique-seeded Jack bean) were cooked (50 minutes). Toxicity study was carried out on the seed during which albino rats were used. Haematological studies were carried out on the blood samples of the albino rats as well as the growth performances of the rats fed the prepared diets were also analyzed. The result of the proximate composition of diets showed that ash, moisture, fat and total energy showed a significant increasing effect (P≤0.05) as the concentration of the processed sample increases in the feed mix, whereas, a significant decreasing effect (P≥0.05) was observed on protein, carbohydrate and crude fibre as the concentration of the cooked seed increases in the feed mix. Protein efficiency ratio (PER) study showed that 75:25 blends of cooked -to -control were considered as intermediate quality seed protein whereas 50:50, 75:25 blends of cooked -to -control feed mix as well as the control diet posses' protein with good quality. The Haematological studies showed specific and selective effect on some albino rats' blood samples which has the ability to cause thromboembolism, hyposplenism and thrombocytosis with possible vascular accidents at higher ratio.