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A considerable amount has been written about the use of metrics to drive business, government and communities towards more sustainable practices. A number of metrics have also been proposed over the past 5U10 years to make chemists aware of the need to change the methods used for chemical syntheses and chemical processes. This paper explores several metrics commonly used by chemists and compares and contrasts these metrics with a new metric known as reaction mass efficiency. The paper also uses an economic analysis of four commercial pharmaceutical processes to understand the relationship between metrics and the most important cost drivers in these processes.

Green Chemistry CONTENTS News & Views G2Editorial Evolution and growth in 2001 G3 Feature Fluorous techniques for the synthesis and separation of organic molecules G8News & Views -G8 Highlights. G10 Super-efficient dyes for the colorations of cotton. G13 Focus on . . . Professor Keith Smith, University of Wales Swansea. G15 Pipe dreams? Shifting the balance towards clean technology.

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