Surgical site infection is a common post-operative complication that is encountered by surgeons and is associated with notable morbidity and mortality. Oral cavity due to the presence of bacteria is more prone to infection and diseases. Even performance under complete sterilization cannot prevent the infection in oral surgeries and the prevalence of infection rate accounts to approximately 10%-15%. Post-operatively oral and maxillofacial surgeries have increased chances of infection due to bacterial load and access to incision site during healing time. The purpose of this research is to review the available information about the types, causes and complication rates of surgical site infection post maxillofacial surgery. Various procedure and patient related factors in oral and maxillofacial surgery contribute to surgical site infections. Procedure's duration and invasiveness as well as bone equipment, biomaterial use, surgical technique, and sterilization practices are some of determinants of surgical site infection. Cellulitis, abscess, maxillary sinusitis, and osteomyelitis are all common postoperative infections. Surgical site infections often result in requirement of additional treatment procedures, prolongs the hospital stay and also negatively affects health of the patient. Efficient interventions by the oral and maxillofacial surgery teams can play a vital role in prevention of such infections. Although surgical site infection is an area of concern for oral and maxillofacial surgeons’ literature on this aspect is quite scarce and very limited studies are available. In future, more clinical and comprehensive research can be beneficial.