Results of a clinicopathologic study of seven cases of a previously unreported disease of minor salivary gland are presented. Necrotizing sialometaplasia is a disease of adults with four of seven patients being in the sixth decade of life. In every case, this benign inflammatory process involved only the tissues covering the hard palate, and, in six instances, it was characterized by ulceration. Lobular necrosis and marked squamous metaplasia of salivary gland are consistent features. Microscopically, necrotizing sialometaplasia shows marked similarity to mucoepidermoid carcinoma, and criteria are presented to aid in distinguishing these two conditions. There have been no recurrences following local surgical excision. Etiologic factors remain obscure.

No abstract

This report presents the clinical and morphological features of a previously unreported distinctive neoplasm of salivary gland origin. It appears to be quite similar morphologically to the syringadenoma papilliferum of sweat gland origin which tends to support the close relationship that exists between neoplasms of salivary and sweat gland origin. We propose the name sialadenoma papilliferum for this distinct tumor.

No abstract