Abstract. In this paper we give a classification of the rank two p-local finite groups for odd p. This study requires the analysis of the possible saturated fusion systems in terms of the outer automorphism group of the possible Fradical subgroups. Also, for each case in the classification, either we give a finite group with the corresponding fusion system or we check that it corresponds to an exotic p-local finite group, getting some new examples of these for p = 3.
Drugâdrug interactions are of significant concern in clinical practice in oncology, particularly in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically exposed to long-term regimens. This article presents the highlights from the âFirst Workshop on Pharmacology and Management of CDK4/6 Inhibitors: Consensus about Concomitant Medicationsâ. The article is structured into two modules. The educational module includes background information regarding drug metabolism, corrected QT (QTc) interval abnormalities, management of psychotropic drugs and a comprehensive review of selected adverse effects of palbociclib and ribociclib. The collaborative module presents the conclusions of the five working groups, each of which comprised five experts from different fields. From these conclusions positive lists of drugs for treating common comorbid conditions that can be safely administered concomitantly with palbociclib and/or ribociclib were developed.
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