The objective of this study was to describe our experience (1373 days of support) with the Berlin Heart Excor (BH) ventricular-assist device (VAD) as bridging to cardiac transplantation in pediatric patients with end-stage cardiomyopathy. This study involved a retrospective observational cohort. Records of patients supported with the BH VAD were reviewed. Data regarding age, sex, weight, diagnosis, preoperative condition, single versus biventricular support, morbidity, and mortality were collected. Criteria for single versus biventricular support and intensive care unit management were registered. The procedure was approved by our Institutional Ethics Committee, and informed consent was obtained. Between March 2006 and March 2010, 12 patients with diagnosis of dilated (n = 10) and restrictive (n = 2) cardiomyopathy were supported. Median age was 56.6 months (range 20.1-165.9); mean weight was 18.3 kg (range 8.5-45); and nine patients were female. Every patient presented with severe heart failure refractory to pharmacological therapy. Biventricular support was necessary in four patients. Nine patients underwent heart transplantation. No child was weaned off the BH VAD because of myocardial recovery. Mean length of support was 73 days (range 3-331), and the total number of days of support was 1373. Three patients had fatal complications: 2 had thrombo-hemorrhagic stroke leading to brain death, and one had refractory vasoplegic shock. The BH VAD is a useful and reasonable safe device for cardiac transplantation bridging in children with end-stage heart failure. Team experience resulted in less morbidity and mortality, and time for implantation, surgical procedure, anticoagulation monitoring, and patient care improved.
Objective:To describe the complications associated with heart surgery, compare them to a reference population, and identify mortality risk factors. Patients and methods: Retrospective and descriptive study. All patients who underwent surgery at Hospital Garrahan in the 2013-2015 period were included. Age, weight, procedure, mechanical ventilation, length of stay in days, morbidity, and course were recorded. Renal failure requiring dialysis, neurological deficit, permanent pacemaker, circulatory support, phrenic nerve or vocal cord palsy, reoperation, wound infection, chylothorax, and tracheotomy were considered morbidities. A descriptive, statistical analysis by risk category was done using the Society of Thoracic Surgeons (STS) morbidity score. Results: 1536 patients, median age: 12 months (interquartile range [IQR] 25-75: 3-60), weight: 8 kg (IQR 25-75: 4.4 to 17.5), mortality: 5%. A total of 361 events were recorded in 183 patients. An unplanned reoperation was the most common event (7.2%); the rest occurred in ≤ 3% of patients. Compared to patients without complications, patients who had events required more days on mechanical ventilation: 9.95 ) versus 1.8 (IQR 2575: 1.46-2.14), p < 0.00001; a longer length of stay: 28.8 (IQR 25-75: 25.1-32.5) versus 8.5 (IQR 25-75: 7.9-9.2), p < 0.0001; and had a higher mortality: 19.6% versus 3.1% (RR: 4.58, 95% CI: 3.4 to 6.0), p < 0.0001. Circulatory support and renal failure were associated with a higher mortality. Conclusions: An unplanned reoperation was the most common event. Patients with complications required more days on mechanical ventilation and a longer length of stay and had a higher mortality. Circulatory support and renal failure were associated with a higher mortality.
Morbilidad en cirugía de cardiopatía congénita en un hospital público en ArgentinaMorbidity in congenital heart surgery in a public hospital in Argentina a. Unidad de Cuidados Intensivos. b. Servicio de Cirugía Cardiovascular. Hospital de Pediatría "Prof. Dr. Juan P. Garrahan", Buenos Aires, Argentina. Correspondencia:Dra. María Althabe: maria.althabe@gmail.com Financiamiento:Ninguno que declarar. Conflicto de intereses:Ninguno que declarar.Recibido: 3-4-2017 Aceptado: 9-8-2017 RESUMEN Objetivo: Describir las complicaciones asociadas a cirugía cardíaca, compararlas con una población de referencia e identificar factores de riesgo de mortalidad. Pacientes y métodos: Estudio retrospectivo, descriptivo. Se incluyeron todos los pacientes operados en 2013-2015 en el Hospital Garrahan. Se registró edad, peso, procedimiento, ventilación mecánica, días de internación, morbilidad y evolución. Se consideró morbilidad la insuficiencia renal con diálisis, déficit neurológico, marcapaso permanente, asistencia circulatoria, parálisis frénica o de cuerdas vocales, reoperación, infección de herida, quilotórax y traqueotomía. Se realizó un análisis estadístico descriptivo y por categorías de riesgo utilizando la escala de morbilidad de la Sociedad de Cirugía Torácica (Surgical Thoracic Society, STS). Resultados: 1536 pacientes, mediana de 12 meses (rango intercuartílico -RIC-25-75: 3-60), peso de 8 kg (RIC25-75: de 4,4 a 17,5), con mortalidad de 5%. Se registraron 361 eventos en 183 pacientes. La reoperación no planificada fue el más frecuente (7,2%); los restantes ocurrieron en ≤ 3% de los pacientes. En comparación con los pacientes sin complicaciones, los pacientes con eventos tuvieron más días de ventilación mecánica: 9,24) vs. 1,14), p< 0,00001; mayor internación: 28,8 (RIC25-75: 25,1-32,5) vs. 8,5 (RIC25-75: 7,9-9,2), p <0,0001; y mayor mortalidad: 19,6% vs. 3,1%(RR 4,58;IC95%: de 3,4 a 6,0), p <0,0001. La asistencia circulatoria e insuficiencia renal se asociaron con mayor mortalidad. Conclusiones: La reoperación no planificada fue el evento más frecuente. Los pacientes con complicaciones tuvieron más días de ventilación mecánica, de internación y mayor mortalidad. La asistencia circulatoria y la insuficiencia renal se asociaron con mayor mortalidad.
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