BackgroundThe use of reliable and valid self-report questionnaires to identify drug use disorders (DUD) is a strategy that has shown usefulness for screening. One of the instruments more used for detection is the Drug Abuse Screening Test (DAST). The psychometric properties in the 20-and 10-item versions have been evaluated in other countries but in Mexico the psychometric and diagnostic properties of both versions are yet to be evaluated.

Tight junctions were altered in HPMCs from dialyzed patients. The HT monolayer has lower TER than LT, which might be associated with the peritoneal permeability in these patients. ATRA might be a therapeutic alternative to maintain mesothelial integrity, since it improved TJ localization and expression.

International studies report the availability of strategies and public inicitatives on prevention and treatment of addiction in Latin America. These studies also report established networks of public and private services that include prevention and detoxification programs, outpatient and residential treatment, and also social reintegration initiatives. However, despite these advances, information on the evaluation of the progress, results and impact of these programs is limited.

Substance use related problems, clinical features, and addiction severity reported by treatment seekers are important characteristics to take into account when planning treatment as they facilitate tailoring treatment to meet patients' needs.

IntroductionEvidence shows a lag in adoption of evidence-based practices (EBPs) for substance abuse treatment and supports the need for studying the factors involved in this worldwide problem.