To the Editors:Papular-purpuric "gloves and socks" syndrome (PPGSS) was first reported as a distinct entity by Harms et al. in 1990 (l), but Bagot and Revuz (2) were the first to demonstrate serologic evidence of a parvovirus B 19 primary infection.We saw an 1 1 -year-old girl with a five day history of progressive symmetrical, sharply marginated, pruritic and purpuric swelling of the hands, wrists, feet and ankles. These signs were accompanied by fatigue, hyporexia, myalgias, arthralgias, and laterocervical and submaxillary lymphadenopathy. A week later a petechial and papular rash appeared within erythematous skin and extended to the distal portion of the legs (Fig. 1). A petechial palate1 exanthem was also seen in the oral cavity. Her temperature was 39°C. There was no hepatosplenomegaly .Laboratory studies revealed a leucocytic count of 5.1x 10"L with 73% segmented, 15% lymphocytes, 8% monocytes, and 4% eosinophils. Bacteriologic blood, urine, and throat cultures were negative. A S 0 titer was 200 UI/ml. ELISA was positive for antiparvovirus B 19 IgM and negative for IgC. Serologic tests for rubella and
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