Российский научно-исследовательский противочумный институт «Микроб», Саратов 2 центр гигиены и эпидемиологии в Саратовской области, Саратов, Россия epidemic actiVitY of modern anthropourgic plague foci and factors determining this actiVitY (BY the eXample of Vietnam) sludsky a. a. 1 , Kuznetsov a. a. 1 , matrosov a. n. 1 , Boiko a. V. 1 , Kouklev e. V. 1 , tarasov m. a. 2 1 russian research anti-plague institute «microbe», saratov 2 center of hygiene and epidemiology in the saratov region, saratov, russia

Purpose: To investigate the stress-strain state of a thin homogeneous isotropic plate in the form of a sector by numerical-analytical method. To consider the possibility of using computer algebra systems (CAS) to calculate sectoral plates operating under bending due to a transverse load. To demonstrate the effectiveness of applying one of these CASs through the example of the Maple system for calculations using the Ritz method — performing analytical transformations when calculating the integral that determines the total potential energy functional, forming and solving the main resolving system of linear algebraic equations with respect to unknown numerical coefficients in the formula approximating the deflection of the plate, visualization of the obtained solution. Methods: A direct method is used to solve the variational problem of minimizing the functional of the total potential energy of deformation of a thin homogeneous isotropic plate in the form of a sector — the Ritz method. The solution is constructed in the form of a series in terms of basis functions. As basis functions, polynomial functions are chosen that exactly satisfy all boundary conditions. Results: An approximate numerical-analytical solution has been obtained for the problem of bending a sectoral plate in the form of a quarter of a circle, clamped along the contour and loaded with a uniformly distributed load. The effectiveness of using the Maple analytical computing system for solving the problem of bending a sectoral plate by the variational Ritz method is demonstrated. It is shown that the resulting solution quickly converges both for deflection and for bending moments and stresses. Practical significance: The algorithm proposed in the article for solving the problems of bending sectoral plates can be recommended for practical use in determining the stress-strain state of such plates.

Our research aim was to estimate efficiency of emergency disinsection and deratization that were accomplished to reduce risks of diseases among population in Gorno-Altaiskiy high-mountain natural plague focus. The research was performed in 2016–2021 in Gorno-Altaiskiy high-mountain plague focus which is the northern part of Sailygem cross-border natural focus located both in Russia and Mongolia. Zoological, epizootologic, epidemiological and statistical research procedures as well as GIS-tools were applied to collect and analyze research data. Epidemiologic surveillance over plague in the focus has been accomplished since 1961. Prior to 2011 only rhamnoso-positive strains of the plague microbe with selective virulence were found here, belonging to the Central Asian subspecies Yersinia pestis altaica, circulating mainly in the population of the Ochotona pallassi. Given that, the focus was believed to have low epidemic potential. Since 2012 highly virulent strains of the basic plague microbe Yersinia pestis ssp. pestis started to occur in populations of Marmota baibacina and other carriers. As a result, starting from that period of time, epidemiologic status of the focus changed and it led to 3 cases of bubonic plague among humans in 2014–2016. Disinsection and deratization remained the major components in anti-epidemic activities aimed at non-specific plague prevention. In 2016–2021 fields disinsection covered a total square equal to 162.7 km2; disinsection in settlements, 127.3 thousand m2; deratization in settlements, 461.7 thousand m2. An approach involving disinsection only on land spots that were considered epidemically hazardous was first implemented; such land spots were around livestock breeders’ camps located within boundaries of detected epizooties. Efficiency of fields disinsection amounted to 94.6; disinsection in settlements, 100 %; deratization in settlements, 88.0 %. Population of plague vectors and carriers was controlled bearing in mind environmental aspects in regulating numbers of animals and compliance with environmental protection requirements. Deratization and disinsection, together with other activities aimed at plague prevention, provide epidemiologic welfare in the focus and reduce its epizootic activity.

Our research aim was to estimate efficiency of emergency disinsection and deratization that were accomplished to reduce risks of diseases among population in Gorno-Altaiskiy high-mountain natural plague focus. The research was performed in 2016–2021 in Gorno-Altaiskiy high-mountain plague focus which is the northern part of Sailygem cross-border natural focus located both in Russia and Mongolia. Zoological, epizootologic, epidemiological and statistical research procedures as well as GIS-tools were applied to collect and analyze research data. Epidemiologic surveillance over plague in the focus has been accomplished since 1961. Prior to 2011 only rhamnoso-positive strains of the plague microbe with selective virulence were found here, belonging to the Central Asian subspecies Yersinia pestis altaica, circulating mainly in the population of the Ochotona pallassi. Given that, the focus was believed to have low epidemic potential. Since 2012 highly virulent strains of the basic plague microbe Yersinia pestis ssp. pestis started to occur in populations of Marmota baibacina and other carriers. As a result, starting from that period of time, epidemiologic status of the focus changed and it led to 3 cases of bubonic plague among humans in 2014–2016. Disinsection and deratization remained the major components in anti-epidemic activities aimed at non-specific plague prevention. In 2016–2021 fields disinsection covered a total square equal to 162.7 km2; disinsection in settlements, 127.3 thousand m2; deratization in settlements, 461.7 thousand m2. An approach involving disinsection only on land spots that were considered epidemically hazardous was first implemented; such land spots were around livestock breeders’ camps located within boundaries of detected epizooties. Efficiency of fields disinsection amounted to 94.6; disinsection in settlements, 100 %; deratization in settlements, 88.0 %. Population of plague vectors and carriers was controlled bearing in mind environmental aspects in regulating numbers of animals and compliance with environmental protection requirements. Deratization and disinsection, together with other activities aimed at plague prevention, provide epidemiologic welfare in the focus and reduce its epizootic activity.