Thermal-Hydraulic (TH) codes are used to simulate the response of nuclear safety systems under transient and accident conditions. The outcomes of the simulations are used to verify the safety margins required for safe operation and make decisions on how to maintain them. In this work, a novel Expert System (ES) based on Regional Sensitivity Analysis (RSA) is developed to guide a system undergoing an accident scenario towards the safest conditions in the optimal number of operation. The ES proceeds by firstly identifying the (uncertain) system controllable variables (i.e., control rods position, feedwater flow rate, void fraction inside the steam generator, etc.) that most affect the system response by RSA; then, the limit-state function is calibrated on a dataset of outcomes of TH code runs and the system failure boundary (i.e., the limit surface) is defined on the set of (uncertain) TH input variables. Application of the ES is firstly shown with respect to an analytical case study that artificially simulates the response of a NPP to an accident scenario and, then, to a practical case study concerning the response of the pressurizer of a Pressurized Water Reactor (PWR).
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