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Over the past five years, efforts to set up a Brazilian clinical trials registry have progressed from early discussions in academic forums through to the establishment of the registry as a web-based computer platform. This article describes the process of developing and introducing the Brazilian Clinical Trials Registry (ReBEC), and its relationship with the authorities that regulate clinical research in Brazil. The Brazilian Clinical Trials Registry and the multilingual, free and open source, internet-based software developed to manage it are outcomes of partnerships among Brazilian federal and international health agencies. Information for describing the technical and operational dimensions of Rebec was drawn from technical documents and the records of the OpenTrials software development team and the ReBEC executive and advisory committees, which are available in free-access repositories. The Brazilian Clinical Trials Registry was launched in December 2010, and approved as a primary registry of the WHO ICTRP network in April 2011. ReBEC's arrival on-line and its acceptance as an ICTRP primary registry is a significant step in consolidating a policy of free access to information on clinical research in Brazil.

The knowledge deficit model with regard to the public has been severely criticized in the sociology of the public perception of science. However, when dealing with public decisions regarding scientific matters, political and scientific institutions insist on defending the deficit model. The idea that only certified experts, or those with vast experience, should have the right to participate in decisions can bring about problems for the future of democracies. Through a type of "topography of ideas", in which some concepts from the social studies of science are used in order to think about these problems, and through the case study of public participation in the elaboration of the proposal of discounts in the fees charged for rural water use in Brazil, we will try to point out an alternative to the deficit model. This alternative includes a "minimum comprehension" of the scientific matters involved in the decision on the part of the participants, using criteria judged by the public itself.

From a climate change perspective, the governance of natural common-pool resources—the commons—is a key point in the challenge of transitioning to sustainability. This paper presents the main strategic advances of the São Paulo Urban Living Laboratory (ULL) regarding Food, Energy and Water (FEW Nexus) analysis and modelling at the border of a high biodiverse forest in a peri-urban region in southeast Brazil. It is a replicable and scalable method concerning FEW governance. The FEW Nexus is an analytical guide to actions that will enable a colossal set of innovative processes that the transition to sustainability presupposes. Sustainable governance of the FEW dimensions, seen as an innovation-based process, is approached by a decision making tool to understand the past and future dynamics of the system. The governance framework is based on a multi-criteria and multi-attribute set of sustainability-relevant factors used as indicators to model complex system dynamics (SD) and the stakeholders’ future expectations through a Delphi approach. Based on the three main dimensions of the Ecosystem Services Approach—Physical and Material Conditions, Attributes of Communities, and Rules-in-Use—the tool comprises thirteen specific sustainability indicators such as water and carbon footprints, land use social development, payment for ecosystem services, and land use gain indices. Its development was designed to generate a long-term network of socioenvironmental stakeholders’ decision making processes and collective learning about a higher level of sustainable systems. System Dynamics modelling demonstrates the associations between sustainability indicators and the impacts of payment for ecosystem services on the land use social development index, or on the trophic state index. The Delphi foresight approach, using the Promethee-Gaia method, allows us to understand the positions of multiple agents regarding the transition process. In this context, decision making tools can be very useful and effective in answering the “how to” questions of ULLs and paving the way for transition, providing collective planning and decision support frameworks for sustainability transition management.

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