Fifteen NHS occupational health departments from the Wessex and Oxford regions took part in an audit of the management of sharps injuries and contamination incidents. Data were collected prospectively for a series of 1102 incidents notified over a nine-month period. The rates of notified incidents for each department ranged from 9 to 44 incidents per 1000 staff members per year. The proportion of injured employees who were naturally immune to hepatitis B or had completed a full course of vaccination against the infection ranged from 57 to 83%, with the main shortfall occurring in ancillary workers. Some departments rarely stored source serum, while others did so in the majority of cases. The proportion of cases where the injured person was known to have had hepatitis B antibody levels > 100 IU/l within the past 12 months, or underwent immediate antibody assessment or had an immediate vaccination against hepatitis B varied from 26 to 97%, with a median of 68%. On the basis of these findings, the audit group has set targets against which performance will be re-assessed in a follow-up exercise.
Implantation of electrodes in the brain has been used as a clinical tool for decades to stimulate and record brain activity. As this method increasingly becomes the standard of care for several disorders and diseases, there is a growing need to quickly and accurately localize the electrodes once they are placed within the brain. We share here a protocol pipeline for localizing electrodes implanted in the brain, which we have applied to more than 260 patients, that is accessible to multiple skill levels and modular in execution. This pipeline uses multiple software packages to prioritize flexibility by permitting multiple different parallel outputs while minimizing the number of steps for each output. These outputs include co-registered imaging, electrode coordinates, 2D and 3D visualizations of the implants, automatic surface and volumetric localizations of the brain regions per electrode, and anonymization and data sharing tools. We demonstrate here some of the pipeline’s visualizations and automatic localization algorithms which we have applied to determine appropriate stimulation targets, to conduct seizure dynamics analysis, and to localize neural activity from cognitive tasks in previous studies. Further, the output facilitates the extraction of information such as the probability of grey matter intersection or the nearest anatomic structure per electrode contact across all data sets that go through the pipeline. We expect that this pipeline will be a useful framework for researchers and clinicians alike to localize implanted electrodes in the human brain.
The Archives de la Préfecture de Police de Paris have served as an important source base for historians of both female prostitution and male homosexuality during the nineteenth century. Although the archives often place these two forms of sexual marginality in the same series, cartons, and dossiers, historians have almost always treated the two as distinct social categories. This article argues that this separation results from an overreliance on the modern sexual identity categories that serve as our point of departure. Instead, we should approach the archive without identifying with it in order to formulate a vision of the sexual past that may or may not reflect our own sexual organization. In dialogue with a broader discourse that conflated male same-sex sexual activity with female prostitution, these archives participate in the production of a sexual category that has as much to do with the selling of sex as it does with same-sex sexual desire. Les historiens de la prostitution féminine et de l'homosexualité masculine au dix-neuvième siècle ont abondamment utilisé les archives de la Préfecture de police de Paris. Bien que les archives situent souvent de ces deux formes de marginalité sexuelle dans les mêmes séries, cartons, et dossiers, les historiens les ont presque toujours traitées comme des catégories sociales distinctes. Le présent article affirme que cette séparation repose sur une dépendance des catégories qui fournissent le point de départ des enquêtes historiques. Le refus de s'identifier à l'archive est une étape nécessaire pour formuler une vision du passé sexuel qui peut—ou pas—refléter notre propre organisation sexuelle. En dialogue avec un discours combinant les activités sexuelles entre hommes avec la prostitution féminine, ces archives participent en effet à la production d'une catégorie sexuelle qui a autant à voir avec le commerce du sexe qu'avec le désir homosexuel.
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