Aim. To evaluate the volume of antithrombotic therapy (ATT) at the prehospital stage in connection with the risk of thromboembolic complications, and also to study the dynamics of the frequency of administration of oral anticoagulants (ОAC) in patients with atrial fibrillation (AF) in 2015-2017.Material and methods. The registry included 562 patients with AF at the age of 18 years and older, hospitalized in the cardiology department during 2015-2017. The registry did not include patients with AF and mechanical heart valves, mitral stenosis. The diagnosis of AF was established in accordance with the current recommendations. All patients had an assessment of the risk of thromboembolic complications on the CHA2DS2-VASc scale, the risk of bleeding on the HAS-BLED scale. The incidence of ATT at the prehospital stage was assessed depending on the risk of thromboembolic complications based on patient questioning and analysis of medical records. In addition, an assessment of the dynamics of the frequency of the OAC prescription during 2015-2017 was conducted.Results. The overwhelming majority of patients with AF (96.1%) belonged to the group of high-risk of cardioembolic strokes according to the CHA2DS2-VASc scale and had indications for OAC therapy. The frequency of OAC prescription in patients with AF who were admitted to the cardiology department was 32% at the prehospital stage, of which 19.8% of patients took warfarin and 12.2% – direct OAC. The target level of the international normalized ratio (from 2.0 to 3.0) at the time of hospitalization was observed only in 33.6% of patients taking warfarin. Over the observation period, there was a tendency to increase the frequency of OAC prescription from 30% in 2015 to 38.4% in 2017.Conclusion. Only 32% of patients with AF and high risk of thromboembolic complications received adequate antithrombotic therapy at the prehospital stage. According to the registry the frequency of OAC prescription in patients with AF during 2015-2017 increased by 8.4%. At the same time, there was a significant increase in the frequency of direct OAC prescription.
Изучена частота встречаемости инсульта и системных эмболий, а также адекватность антитромботической терапии (АТТ) у 664 пациентов с неклапанной фибрилляцией предсердий (ФП) и перенесенным острым нарушением мозгового кровообращения (ОНМК), по данным госпитального регистра КРАФ. Анализ показал, что частота тромбоэмболических осложнений у больных с ФП увеличивается с возрастом, при этом у женщин частота случившихся ОНМК достоверно выше, чем у мужчин. Адекватную терапию ОАК на догоспитальном этапе принимали менее 50% пациентов с перенесенным ОНМК.
Изучена частота встречаемости сердечной недостаточности и системных эмболий, а также адекватность антитромботической терапии (АТТ) у 664 пациентов с неклапанной фибрилляцией предсердий (ФП), по данным госпитального регистра КРАФ. Распространенность СН по данным регистра КРАФ составила 52, 7% (57,2% мужчин и 49,2% у женщин (p=0,03)). Частота встречаемости СН у пациентов с ФП увеличивалась с возрастом. Адекватную терапию ОАК на догоспитальном этапе принимали 39,1% пациентов с ФП и СН.Ключевые слова: фибрилляция предсердий; сердечная недостаточность; антитромботическая терапия.The frequency of occurrence of heart failure and systemic emboli was studied, as well as the adequacy of antithrombotic therapy (ATT) in 664 patients with non-valvular atrial fibrillation (AF), according to the KRAF hospital register. The prevalence of HF according to the KRAF registry was 52.7% (57.2% of men and 49.2% of women (p = 0.03)). The frequency of occurrence of HF in
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