The relationship of COVID-19 and pregnancy implies a novel clinical condition, information regarding the true medical picture is currently being collected. The present work aims to carry out a review of the most prominent publications on COVID-19 and Pregnancy: epidemiology and clinical evolution based on currently available evidence.
The fetus and placenta are an immunologically privileged unit, whose physiological changes during pregnancy intervenes in the behavior against SARS-CoV- 2, describing a theoretical potential teratogenic damage due to receptors ACE-2 expression, necessary for SARS-CoV-2 intracellular transport in the epiblast, vital in organogenesis, as well as the current pharmacological therapy teratogenic effects, abortions, and fetal demise.
Objective: To design a nomogram by percentiles of the fetal right liver lobe measurement in pregnant between 16 and 40 weeks of gestation who attend the Maternidad Concepción Palacios in the period between March and August 2020. Methods: A prospective, descriptive and cross-sectional study was conducted that included 350 patients with informed consent, were measured fetal right liver lobe, related to gestational age, based on the date of the last menstruation or ultrasound of the first trimester, and associated with weight, size and maternal body mass index. Results: An average fetal right liver lobe measurement of 37.42 ± 12.03 mm (Min 13 and max 62 mm) was obtained. The regression analysis yielded a correlation coefficient between fetal right liver lobe size and gestational age of 0.950. The determination coefficient obtained was 0.903. Depending on the result of the variance analysis, there is an association between the two variables (p-0.000). A fetal right liver lobe increase measurement of + 1,585 per week (95% CI - 1,531 - 1,640) (p-0.000) was obtained. The percentile nomogram was constructed. There was no relationship between the measurement and maternal weight and height, but there was with the body mass index. Conclusion: The fetal right liver lobe, as an expression of the liver measure, grows relative to the increase in gestational age and this allowed to design a nomogram per percentiles.
El embarazo ectópico abdominal tiene baja incidencia de 1 por cada 10 000 embarazos, representa el 1 % de los embarazos ectópicos. Se clasifica en ectópico abdominal primario o secundario de acuerdo a su génesis de instauración. Se presenta una paciente de 35 años, IIG IA, con antecedente de embarazo ectópico tubárico diagnosticado a las 8 semanas de gestación, no resuelto, quien ocho semanas después consultó por dolor y sangrado. Ingresó con diagnóstico de embarazo abdominal, con ecografía que mostró feto en cavidad abdominal e imagen sugestiva de hematoma que abarcaba la región posterior del útero, ovario derecho, omento, intestino delgado y colon transverso. Se practicó laparotomía media infraumbilical con extracción de feto, salpingectomía izquierda, disección del tejido trofoblástico, omentectomía y apendicectomía. Posteriormente, se indicó tratamiento médico con metotrexato, con egreso en condiciones satisfactorias y control por consulta externa. Palabras clave: Embarazo ectópico, Embarazo abdominal, Metotrexato
La actual pandemia COVID-19 constituye una dinámica epidemiológica con implicaciones inherentes a la rápida extensión de la enfermedad y sus vastas consecuencias en la Salud Pública. La población gestante constituye un grupo de atención que no escapa del riesgo. Se presenta una revisión de la evidencia a la fecha sobre la práctica segura y la utilidad de los estudios de imagen (radiología de tórax, tomografía computada y ultrasonido pulmonar) en el manejo y seguimiento de la patología respiratoria producida por SARS-CoV-2. Palabras clave: COVID-19, SARS-CoV-2, Embarazo, Radiología de tórax, Tomografía computada de tórax, Ultrasonido pulmonar, Práctica segura.
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