No abstract

-The aim of the present study was to examine, for the first time in pigs, the dosedependent effect of arginine (ARG) on growth hormone (GH) and insulin release and the effect of the combined ARG and aspartic acid (ASP) treatment on GH and insulin release. ARG (0.5 or 1 g/kg body weight) with or without an equimolar supplement of ASP (0.38 or 0.76 g/kg, respectively) was administered in piglets via the duodenum. ARG

Summary -In human, arginine (ARG) induces growth hormone (GH) release, probably via a decrease in somatostatinergic tone. To assess the mechanism by which ARG mediates GH release in pigs, the effects on plasma GH release of ARG ( 1 g/kg body weight, infused between times -15 and -5 min), growth hormone-releasing hormone (GHRH, 2 pg/kg, at time 0 min) and neostigmine, a cholinesterase inhibitor (NEO, 50 arginine / growth hormone-releasing hormone / néostigmine / hormone de croissance / porc