Background: Several recent studies have indicated that total antioxidant capacity (TAOC) of plasma seems to be compromised in chronic periodontitis (ChP). The aim of this study is to investigate plasma TAOC in patients with ChP and to assess the effects of vitamin C as an adjunct to non‐surgical periodontal treatment.
Methods: The study population consisted of 60 subjects: 30 diagnosed with ChP and 30 matched controls. Furthermore, patients from the ChP group were randomly allocated into ChP1 (15 patients received non‐surgical treatment with adjunctive dose of vitamin C) and ChP2 (15 patients received non‐surgical periodontal treatment alone). Plasma TAOC levels were measured by an ABTS assay at baseline and 1 month post‐therapy.
Results: Plasma TAOC levels were significantly lower in ChP patients than controls (P <0.001). The periodontal therapy resulted in increasing plasma TAOC and improvements in clinical measures among both ChP1 and ChP2 groups (P <0.001). However, the adjunctive dose of vitamin C did not offer additional effect (P >0.05).
Conclusions: ChP is significantly associated with lower levels of plasma TAOC. The non‐surgical periodontal therapy seems to reduce the oxidative stress during the periodontal inflammation. However, the use of adjunctive vitamin C still needs further investigation.
A primary spinal Ewing sarcoma is extremely rare to be found. To the best of our knowledge, it is the first reported case for bilateral foot drop as a prodromal symptom of sacral Ewing sarcoma. The case, we are presenting, is of an 18-year-old athletic female, who was presented to the emergency department suffering from sudden severe low back pain radiated to the lower limbs, associated with bilateral foot drop and later urinary incontinence. Following the indicated surgery and subsequent histopathology study, we diagnosed this rare type of tumors. In the following article, we are describing the clinical presenting features of this tumor and discussing the clinical aspects.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.