Background: Chemotherapy is used to treat approximately 70% of cancer patients. Oral complications secondary to chemotherapy are recorded in about 80% of hemato–oncologic patients, these complications affect the patients’ quality of life and could sometimes be fatal. Objective: To describe the oral manifestations secondary to chemotherapy medication in hemato-oncologic patients and to determine which of those oral manifestations is more common. Patients and Methods: A sample of 190 patients presented to Nanakali Hospital for blood- related diseases and cancer in Erbil. The age range of the patients was 3-80 years, (mean 38.35 ± 22.62). Various types of malignancies, types of chemotherapy, and oral manifestation secondary to chemotherapy were recorded. Results: The most common type of cancer presented was leukemia (37.9%). In patients undergoing chemotherapy, the recorded oral manifestation was mucositis, xerostomia, fungal and viral infection. Mucositis was the most common, being recorded in 46.3% of the subjects. Conclusion: The results highlight the importance of the presence of a specialist in Oral and Maxillofacial Medicine working in coordination with the medical team to take care of the patients before, during and after chemotherapy. This multidisciplinary team can decrease the frequency of occurrence of oral manifestations, and can even assist in early diagnosis and management of oral lesions in case oral manifestation occurs. Keywords: Oral manifestation, chemotherapy, hematology-oncology patient, mucositis, fungal infection, xerostomia, viral infection
Background and Objectives: Recurrent aphthous stomatitis is common oral condition, characterized by multiple, recurrent, small, round, or ovoid ulcers with circumscribed, erythematous haloes, and yellow or grey floors. Its etiology and pathogenesis is not entirely clear linked to systemic diseases and among these, anemia, iron deficiency, folic-acid, and vitamin B12 deficiencies. The aim of this study to investigate the association between recurrent aphthous stomatitis and hemoglobin, serum ferritin, folic acid, and vitamin B 12 deficiency.Patient and Methods: This prospective cross sectional case control clinical study was conducted on 50 patients with recurrent aphthous stomatitis. The control group composed of 50 healthy age and sex-matched subject. The patient demography about family history of recurrent aphthous stomatitis, and smoking was recorded, also the hemoglobin, serum levels of ferritin, folic acid, and vitamin B 12 has been investigated. Results:The low hemoglobin was reported in 30% and vitamin B 12 deficiency in 31% of the patient so low hemoglobin and B 12 deficiency have significant correlation with recurrent aphthous stomatitis. Patients with low hemoglobin, vitamin B 12 deficiency , positive family history, and non smoker have been found to have the highest risk for having recurrent aphthous stomatitis. Conclusion:Recurrent aphthous stomatitis is a multifactorial disease. Positive family history, low hemoglobin level , vitamin B12 deficiency, and nonsmoking status are among the important predisposing factors. Routine hematological screening and tests for iron status, folic acid, and vitamin B12 status should be assessed in all patients with recurrent aphthous stomatitis.
Prevalence studies on oral conditions affecting children are rare worldwide, and none of them was conducted in in Erbil/Kurdistan region/Iraq. The aims in the this study were to determine the prevalence and distribution of oral conditions which include both lesions and normal variations in group of patients referred to a main, public specialized poly clinics dental center. A prospective cross-sectional study was performed, the including data collected were age, gender, and site of a condition. The examination of the patients was performed under standardized conditions; using artificial light, disposable gloves, retractors, and mirror with sterile gauze to hold tip of the tongue. Statistical analysis was performed using Statistical Package for the Social Sciences (SPSS) version 22; Fisher’s exact test; and Chi-square test. A sample of 520 children, aged range (0–13) years included in this study, 265 (51.0%) were males and 255 (49.0%) were females, divided into three age groups; 100 (19.2%) were <5 years, 274 (52.7%) were 5–9 years, and 146 (28.1%) were 10–13 years. The prevalence of oral conditions was significantly higher in 5–9 years (52.7%). The most commonly clinically diagnosed oral conditions were fissure tongue (13.1%), followed by gingivitis (9.0%) and dentoalveolar sinus (8.3%). As a first study in this age group in Erbil/Kurdistan region/Iraq, oral conditions are relatively common in the sample examined; dentist and dental practitioner should be aware for their recognition and referral for management.
Oral mucositis is a complication of systemic anticancer therapies. This study aimed at investigating the use of ice cubes and sodium bicarbonate mouthwash as a preventive and a treatment measure for oral mucositis in patients receiving systemic anticancer therapies. The two measures were given to 50 patients, 24 of whom already had oral mucositis at Oncology Department in Rizgary Teaching Hospital in Erbil/ Iraq. Patients’ grades for oral mucositis were recorded before and after receiving the two measures. After treatment of the 24 patients with Oral Mucositis, the number decreased to 9 patients. The grades of patients’ oral mucositis also decreased to lower grades The two measures were effective but sodium bicarbonate mouthwash was more significant effective as a treatment and preventive measure for oral mucositis (p=0.044) than ice cubes (p=0.022).
Background: Denture induced stomatitis often referred to as denture sore mouth and prosthetic stomatitis, denotes inflammation of the oral mucosa, particularly the palatal mucosa that are in close contact with the denture base. Objective: To evaluate the prevalence and risk factors of denture induced stomatitis in complete denture wearers attending Khanzad Teaching Dental Center. Patients and Methods: This study included one hundred consecutive upper denture wearers from prosthetic department in Khanzad Teaching Dental Center , the age range of the patients was 39-85 years .Different factors such as age, gender, denture age ,wearing time and hematinic parameters investigated and recorded .The diagnosis of denture stomatitis was done by clinical examination .The data entered and analyzes by (SPSS software version 25). Results: The prevalence of denture stomatitis was 20%. Non significant relashionship in the prevalence of denture stomatitis with age, gender, denture age, wearing time , type of denture and heamtinic deficiency. Conclusion: Because denture stomatitis is the most prevalent inflammatory reaction that affects denture wearers and is typically asymptomatic, it is better to schedule a routine dental check for them to allow early detection of any abnormalities to treat it and the choice of treatment depends on the cause of change. in many denture wearers the removal of traumatic as well as maintaining good oral hygiene and hygiene of dentures produce positive outcomes.
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