Organophosphate pesticides are one of the causes of contamination in animal feed. The cholinesterase enzyme test is used to diagnose toxic exposure due to organophosphate pesticides. Quantitative research with cross sectional survey design used 35 samples of cattle. The study was conducted in March -September 2020. Concentration measurement on cholinesterase enzyme concentrations of blood plasma used the biosystem A15 DGKC-Colorimetric Kinetic method. This study aims to evaluate the concentration of the enzyme cholinesterase as a marker of organophosphate poisoning in cattle. Blood samples were collected from the ventrolateral neck veins of bulls and cows aged 1-7 years which collected from local breeders in the Ogan Ilir area. The results showed that the cattle raised on exposed land by organophosphate pesticides as concentration decreasing indication of cholinesterase enzyme in cows plasma. Cholinestrase enzyme levels in cows were 0.20 ± 0.067 U / ml and bulls were 0.27 ± 0.183 U / ml. The highest concentration of cholinesterase enzyme levels were occurred in cattle aged 2 years, 0.25 ± 0.34 U/ ml and the lowest was in cattle aged 7 years, 0.12 ± 0.04 U / ml.

Herbicides are generally used in the control of weeds in plants. The use of synthetic chemicals such as herbicides is known tohave a negative impact on the environment. This is because the chemicals in the herbicide can kill or poison the organismsthat eat plants that are exposed to these chemicals. Glyphosate is one of the active ingredients of herbicides which is systemic,so it may leave a residue on weeds such as grasses which are usually used as animal feed. The aim of this study is to analyzethe impact of glyphosate residues on changes in the organ tissue of goats (Capra hircus) fed with feed exposed to glyphosatecompounds. The study was conducted using an experimental method with four treatments of glyphosate concentrationincluding control. The treatment consists of four goats with age of 12 months. The results showed that glyphosate treatmentin feed influenced the development and tissue of the goats. The higher the concentration of the residue exposed to the feed,the higher the residual concentration of glyphosate in livestock blood, namely 0.2377 ppm (P1), 0.3118 ppm (P2), and 0.9377ppm (P3), respectively. The results of the observation on livestock organ tissue showed that there was severe damage to theliver and minor damage to the lung, gastric and kidney tissue. The higher the concentration of the residue exposed to thefeed, the higher the residual concentration of glyphosate in livestock blood and causing more damage