Background and objective: Viral Hepatitis Type B&C is serious public health challenge throughout the world.Hepatitis B and C viruses still remain to be the major causes of chronic hepatitis.It is estimated that around 350-400 million people in the world are chronic carriers of HBV, which represents approximately 7% of the total populationwhereas infection with HCV is found in approximately 3% of the world population, which represents 160 million people. Hepatitis B infection has a wide range of seroprevalence in the Mediterranean countries ranging from intermediate (=>2% ) to high prevalence ( =>7%). World Health Organization estimated a prevalence rate for HCV infection of about 4.6% in Eastern Mediterranean in 1999. During the eightieths years of the last century, Iraq was considered to be of intermediate endemicity with hepatitis B as reflected by 3% seroprevalence of HBsAg in normal population. Hepatitis C was found to be of low endemicity among blood donors 0.5%. There were no national wide epidemiological studies regarding the prevalence of hepatitis B&C accordingly we conduct this study to determine the prevalence of both types all over the Iraq. Methods: From the 1 st of January 2005 to 31 st of December 2006, a community based cross-sectional study was conducted all over Iraqi governorates. A total of 9610 persons, recruited by surveying a nationally representative random sample of households were analyzed. A stratified random sample proportional to size of each of the 18 Iraqi governorates, both urban and rural areas were included. Prevalence estimates were therefore weighted and age-adjusted. Five (5ml) of blood samples were taken from the study subjects, and tested for hepatitis B surface antigen, antibody to hepatitis B core antigen antibody to hepatitis B surface antigen and hepatitis C antibodies . Results:The national prevalence rate of HBs Ag was 1.6% and correlated positively with age. The prevalence rate of anti-HBs antibodies was 17%. The prevalence of anti-HBc was 9.7%. The prevalence of anti-HCV was low (0.4%). The prevalence rate of anti-HBs antibodies in <10 years children is only 32.2%, which raise the issue of incomplete coverage of hepatitis B vaccine during the years preceding the study years. Conclusion:The findings revealed that Iraq is of low prevalence with HBsAg.On the other hand,hepatitis C was found to be of very low prevalence. As a marker of exposure to hepatitis B, Anti HBcIgG was found to increase with age.

Hepatitis, an inflammation of the liver, has a number of infectious and non-infectious causes. Two of the viruses that cause hepatitis (hepatitis A and E) can be transmitted through water and food; hygiene is therefore important in their control. First, to assess the importance of HAV and HEV as a possible diagnosis for clinically diagnosed patients with acute viral hepatitis. Second, to assess the prevalence of hepatitis A and E in all provinces of Iraq and study its association with age, gender. This study consisted of two groups: The first group consisted of 2975 patients with a clinical diagnosis of acute viral hepatitis. The second group consisted of a total of 9610 persons, which were recruited by surveying a nationally representative random sample of households. A stratified random sample proportional to size of each of the 18 Iraqi governorates, both urban and rural areas was employed. Blood samples were taken from study subjects. The relative frequency of positive anti-HAV IgM antibodies was 41.0%, while anti-HEV IgM represented 19.4 % of patients with a clinical suspicion of acute viral hepatitis. The prevalence of hepatitis A-IgG antibodies in Iraqi population is 96.4% (95% confidence interval is 96-96.8%), while that of Hepatitis E-IgG antibodies was 20.3 % (95% confidence interval is 19.4-21.2%). The sero-prevalence showed a steady and significant increase with age for hepatitis E, while it showed an obvious increase between the first and second decade of life for HAV. No significant sex variation was observed for HAV, while males had a higher risk (by 15%) for HEV. The after war situation in Iraq is disastrous, due to the damage to water supply infrastructure and its contamination with sewage, Hepatitis A is hyper endemic in Iraq, while hepatitis E is endemic. Among patients with a clinical diagnosis of acute viral hepatitis, two fifths had serologic evidence of type A and another one fifth had type E viral hepatitis.

Using counter immunoelectrophoresis (CIEP), the carrier rate of HBsAg among the Arab Population of Iraq was found to be 2.8% comparted with 5.5% in the Kurd population. The incidence of antigenaemia in laboratory workers, renal dialysis staff and patients, nursing and blood bank staff, and pulmonary tuberculosis and diabetes mellitus patients is also reported. Study of immunoglobulin classes in carriers and in HBsAg-negative controls showed that raised IgG and IgM is more common in the former than in the latter.

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