In this research, an experimental study was performed regarding the heat transfer performance and pressure drop specifications of a Newtonian fluid and a non-Newtonian fluid. To this end, laminar flow of the deionized (DI) water and the aqueous solution containing 0.2 wt.% carboxyl methyl cellulose (CMC) were used as the Newtonian fluid and the non-Newtonian fluid, respectively, in wavy and straight mini-channel cross-flow heat exchangers (CFHE). Each mini-channel cross-flow plate heat exchanger (MCFPHE) was made of three copper plates for the hot and cold sides, which contain 27 mini-channels in parallel. The mini-channel CFHE was examined for Reynolds numbers (Re) in the range of 200 to 1800 and the hot-side inlet temperature was between 40 °C and 50 °C while the cold-side temperature varied in the range of 10 °C to 20 °C. The thermal and rheological properties of the non-Newtonian fluid were investigated. The results showed that for both fluids, the thermal performance of the wavy mini-channel is more than that of the straight mini-channel and, although the pressure drop was intensified, its effect is low at high Re values
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