Diuretic are prescribed to excrete additional extracellular fluids by increasing urine flow, sodium excretion and decreasing hypertension. There is a need to use these drugs in many veterinary treatments, such as oedema and congestive heart failure, udder and pulmonary oedema, ascites and acidosis or alkalosis, as well as dilution and faster excretion of toxins, especially those that are effective on the renal glumerular filtration rate (Pourjafar et al., 2013;Raidal et al., 2014). The function of the current diuretics include: loop, osmotic, potassium retainers and carbonic anhydrate inhibitors. The loop diuretics are very powerful drugs that prevent tubular reabsorption of sodium, chloride and other electrolytes from kidney tubules, increase their excretion and urine flow. Furosemide is considered to be one of the widely used drugs while also having some side effects, particularly serum potassium and sodium depletion (