One-anastomosis gastric bypass is an attractive bariatric procedure. It is effective in weight loss and comorbidity resolution. It is a relatively simple and fast operation with low complication rates that make it a suitable option in super-obese individuals. Although not proven yet, there are some concerns about its long-term safety profile in terms of biliary reflux, marginal ulcer, and esophagogastric malignancy. In this article, we review the technique of this procedure and discuss about some practical surgical highlights. Furthermore, we overview studies performed about this procedure and compare it to some other well-established bariatric operations, while providing a detailed study about the facts related to its outcomes and complications.

Background: Nowadays, esophageal cancer is among the most malignant cancers with high mortality and morbidity. Although reasonable progress in radiotherapy and chemotherapy has been made, still esophagectomy is the main treatment for the disease. Using esophagectomy induces a durable palliation and provides possible cure.

Colon polyps are a relatively common problem which necessitates a colonoscopic polypectomy. It has its own limitations in surgery. Sessile or large polyps or those at unavailable section (ie: in mesenteric border of colon) are not suitable for a colonoscopic approach for excision. Furthermore, in colonoscopic resection, there is a frustrating risk of a colon wall perforation that not diagnosed intraoperatively. By the help of Combined Endoscopic Laparoscopic Surgery (CELS), a more aggressive polypectomy could be done while the colon wall monitored intraoperatively via laparoscopy and there is an appropriate possibility of colon wall repair if any perforation had occurred .This is a new method in diagnostic and curative surgical approaching to nonmalignant colon lesion that needs a coherent cooperation between laparoscopy and colonoscopy for performing a safe colonoscopic polypectomy.