A identificação e prevenção de interações entre medicamentos estão diretamente relacionadas com a segurança do paciente e são de grande importância no ambiente hospitalar. O objetivo deste trabalho foi identificar e avaliar a existência de interações medicamentosas potenciais na farmacoterapia prescrita. Trata-se de estudo observacional, com 308 prescrições de 195 pacientes internados na Unidade de Terapia Intensiva de um hospital de ensino, realizado de agosto a dezembro de 2015. Para identificação das interações utilizou-se a base de dados Micromedex®. Das 308 prescrições analisadas, 101 apresentaram pelo menos uma interação medicamentosa, totalizando 173 interações, referentes a 71 pacientes. Destes, 43 eram do sexo masculino, com idade média de 61,9 anos. A média de internação na unidade foi de 7 dias. Nas 101 prescrições que apresentaram interações medicamentosas, foi prescrito o total de 1.349 medicamentos com média de 13,3 medicamentos/paciente/dia. Identificar essas interações possibilita evitar situações de insucesso terapêutico e toxicidade medicamentosa.

RESUMO ABSTRACTThe aim of this study was to identify and quantify the number of pharmaceutical interventions for pharmacotherapeutic monitoring of patients admitted to the Emergency Unit of a teaching hospital, from March to May 2015, by recording in spreadsheets made by pharmaceutical residents after evaluation of medical prescriptions. 278 prescriptions were evaluated 190 patients, 59% were female. The mean age was 62.9 (± 17.8) years. 52 pharmaceutical interventions, of which 80.8% were accepted were held. Through clinical activities seek to ensure security by detecting errors before they impact the quality of patient drug therapy. The acceptability of found pharmaceutical interventions indicates the need and importance of the clinical pharmacist activities in hospitals working with the healthcare team in patient care, both in the economic point of view, the clinical, ensuring the rational use of medicines, safety and quality treatment.

Este artigo está licenciado sob forma de uma licença Creative Commons Atribuição 4.0 Internacional, que permite uso irrestrito, distribuição e reprodução em qualquer meio, desde que a publicação original seja corretamente citada. ABSTRACT Aims:To describe the methods used in suicide attempts and sociodemographic characteristics of suicidal patients treated at the emergency department of a teaching hospital. Methods: Observational and descriptive study, with active search for electronic medical records of patients treated at the emergency department of a public teaching hospital in the countryside of Rio Grande do Sul, Brazil, from January to December 2015. All cases of suicide attempt were included, regardless of the suicide methods used. Successful suicide cases were not investigated. The statistical analyses included descriptive statistics, univariate analysis, and Pearson's chi-square test.Results: A total of 233 patients treated at the emergency department were referred for psychiatric evaluation, and 122 of them had attempted suicide. The mean age of the suicidal patients was 36.8±14.3 years, (minimum of 14 years and maximum of 88 years) and 74 (60.6%) of them were female. The most common suicide attempt methods were ingestion of medications (72 cases, 59%) and of pesticide (14 cases, 11.5%). Of all patients, 119 (97.5%) lived in Santa Cruz do Sul, predominantly in the urban area (103 patients, 84.4%). Of the 50 (41.0%) referrals, 32 (64.0%) were sent to the Center for Psychosocial Care, 7 (14%) to the Center for Children's and Adolescents' Psychosocial Care, 6 (12%) were admitted to a mental health unit, and 5 (10%) were sent to Psychosocial Care Center for Alcohol and Drug Abuse. Sixty-six (54.1%) patients had no electronic medical records of their outcome after discharge and 6 (4.9%) were lost to follow-up. Conclusions: Most of the treated suicidal patients were young adult females. The most common method of suicide attempt was the ingestion of medications, followed by the ingestion of pesticides.

This is the first report about the antibacterial activity of Diplotropis ferruginea Benth. In this study, the ethanol extract of D. ferruginea was tested for its antimicrobial activity against strains gram-positive and gram-negative. In order to determine the minimal inhibitory concentration, assays were carried out by micro dilution method. The extract was screened for antimicrobial activity, and it showed antibacterial activity against Escherichia coli and Pseudomonas aeruginosa.

O objetivo deste estudo foi avaliar a frequência de exacerbação em pacientes diagnosticados com Doença Pulmonar Obstrutiva Crônica (DPOC) submetidos em Programa de Reabilitação Pulmonar (PRP) em hospital de ensino no interior do Rio Grande do Sul. Estudo transversal com 32 pacientes. A coleta de dados ocorreu em outubro de 2015, através do sistema computadorizado do hospital e banco de dados do PRP. A amostra foi estratificada em grupos, conforme o tempo de permanência no PRP: menos de dois meses (G1), de dois a 12 meses (G2) e mais de 12 meses (G3).Verificou-se que 59,4% eram do sexo masculino com idade média de 63,5 anos (± 6,9). No G1, 50% dos pacientes exacerbaram, no G2, 65% e no G3, 37,5%. Os resultados demonstraram que portadores de DPOC que frequentaram o PRP por tempo superior a 12 meses apresentaram menor frequência e menor intensidade de exacerbação da doença.Descritores: Reabilitação; Doença Pulmonar Obstrutiva Crônica; Exacerbação dos Sintomas.