Metal-oxide nanoparticles have reached a wide range of applications in the last ten years. Titanium dioxide nanoparticles stand out with their unique crystal structure and near-perfect physical and chemical properties at nanoscales (crystal size between 10–100 nm). It has created many applications with its white pigment, semiconductor state, and effective photocatalytic properties, but the synthesis of these nanoparticles is very damaging to nature. Titanium dioxide nanoparticles, which can be synthesized with toxic solvents or high-energy machines, have started to be synthesized by the green synthesis method, which has been a cheap and easy method in recent years. The application areas of these nanoparticles synthesized with renewable resources (leaves, roots, seeds, etc.) are increasing day by day. This article gives information about the synthesis of titanium dioxide nanoparticles with renewable resources and the application of these nanoparticles synthesized by means of chemical and green synthesis methods.