A b s t r a c tChanges in diet, physical inactivity and stress contribute to obesity, cardiovascular disease and atherosclerosis. Literature shows that bioactive compounds may result in benefits to human health. The aim of this study was to evaluate the glycemic, lipid p of Wistar rats treated with and water water twice daily; Tamarindus indicaGroups G1, G2 and G3 received the drinks by intragastric rout. After this period the animals were sedat profile: total cholesterol, HDL also calculated. The results showed a reduction of total cholesterol, LDL weight and atherogenic indices; and increase in the levels of HDL use of mint and tamarind juice can positively affect the biochemical parameters and reduce the atherogenic indexes of Wistar rats.