Background: The development of virtual human models has recently gained considerable attention in biomechanical studies intending to design for ergonomics. The computer-based simulations of virtual human models can reduce the time and cost of the design cycle. There is an increasing interest in finding the realistic posture of the human body with applications in prototype design and reduction of injuries in the workplace. Objectives: This paper presents a generic method based on a multi-objective optimization (MOO) for posture prediction of a sagittal-plane lifting task. Methods: Improved biomechanical models are used to formulate the predicted posture as a MOO problem. The lifting task has been defined by seven performance measures that are mathematically represented by the weighted sum of cost functions. Specific weights are assigned for each cost function to predict both stoop and squat type postures. Some inequality constraints have been used to ensure that the virtual human does not assume a completely unrealistic configuration. Results: The method can predict the hand configuration effectively. Simulations reveal that predicting a squat posture requires the minimization of certain objective functions, while these measures are less significant for the prediction of a stooped posture. Conclusions: In this study, a MOO-based posture prediction model with a validation process is presented. We employed a three-dimensional model to evaluate the applicability of using a combination of seven performance measures to the posture prediction of symmetric lifting tasks. Results have been compared with the available empirical data to validate the simulated postures. Furthermore, the assigned weights are obtained for a range of percentiles from 50% male to 90% female according to the postures obtained by 3D SSPPTM software.

Context: Hyperhidrosis is known to cause numerous individual and social problems with sweating more than the body’s physiological needs. Researchers have discussed the causes of this disease so far; however, factors such as heredity, nervous system defects, infections, and drugs have been introduced as the causes. Evidence Acquisition: Firstly, 127 articles were identified from different databases. After categorizing and removing duplicate papers and reviewing the abstracts and full texts, we selected 50 articles to review and include in this study. Results: Hyperhidrosis is a burdening disorder leading to physical and social problems. Hyperhidrosis patients are not able to efficiently use specific tools such as metallic and electronic devices. Limitations of this disorder show great concern about the performance of military personnel, too. Therapeutic methods such as topical antiperspirants, anticholinergic drugs, surgery, and Botox injections are the therapeutic measures used to treat this disease; each of these treatments is prescribed at different stages of the disease, and the effect of each is observed. Topical treatment is at the forefront of treatment methods for this disease, followed by oral anticholinergic drugs. Iontophoresis is one of the methods considered in the treatment of hyperhidrosis. Besides surgery, Botox injection is one of the effective methods in treating this disease, especially in the palm. Conclusions: This review presents standard treatment methods used in treating hyperhidrosis with particular attention to iontophoresis as an engineering solution to solve health problems. Based on the severity of sweating and the region of hyperhidrosis incidents, there are different solutions to treat hyperhidrosis. Topical and anticholinergic therapies are the most common treatment options. However, there are other more effective treatment methods, such as iontophoresis and Botox delivery. Iontophoresis is effective and has a long-term effect on preventing sweating with fewer side effects. Suction curettage surgery is an invasive method to treat patients with hyperhidrosis.