This paper reviews the past and recent studies on thermocapillarity in relation to microfluidics. The role of thermocapillarity as the change of surface tension due to temperature gradient in developing Marangoni flow in liquid films and conclusively bubble and drop actuation is discussed. The thermocapillary-driven mass transfer (the so-called Benard-Marangoni effect) can be observed in liquid films, reservoirs, bubbles and droplets that are subject to the temperature gradient. Since the contribution of a surface tension-driven flow becomes more prominent when the scale becomes smaller as compared to a pressure-driven flow, microfluidic applications based on thermocapillary effect are gaining attentions recently. The effect of thermocapillarity on the flow pattern inside liquid films is the initial focus of this review. Analysis of the relation between evaporation and thermocapillary instability approves the effect of Marangoni flow on flow field inside the drop and its evaporation rate. The effect of thermocapillary on producing Marangoni flow inside drops and liquid films, leads to actuation of drops and bubbles due to the drag at the interface, mass conservation, and also gravity and buoyancy in vertical motion. This motion can happen inside microchannels with a closed multiphase medium, on the solid substrate as in solid/liquid interaction, or on top of a carrier liquid film in open microfluidic systems. Various thermocapillary-based microfluidic devices have been proposed and developed for different purposes such as actuation, sensing, trapping, sorting, mixing, chemical reaction, and biological assays throughout the years. A list of the thermocapillary based microfluidic devices along with their characteristics, configurations, limitations, and improvements are presented in this review.
The elegance of digital microfluidics is in incorporating high quantities of manipulated micro and nanodroplets on-chip, each of which can be considered a small-volume carrier of various chemical and biological reagents. Therefore, the analysis of on-demand manipulation of these micro and nanocarriers is extremely important in developing an optimized lab on a chip. In this work, passive coalescence and mixing between two trapped, squeezed nanodroplets inside a closed microfluidic device was investigated. The droplets are composed of glycerol dyed in blue and red, dispersed inside oleic acid as the carrier oil. A microwell with a circular cross section was fabricated on the top wall of the microchannels to trap the first droplet for increasing the mixing precision and minimizing the viscous shear stress imposed on the droplets from the channel walls. The energy minimization theory was used to develop a parametric study for this trapping technique and to choose the optimum design parameters for droplet trapping in terms of efficiency. Image processing was performed on the snapshots of the trapped glycerol nanodroplets during mixing. Growth in passive mixing percentage was demonstrated to be asymptotical and was formulated with an empirical equation of exponential form as a function of the passive mixing relaxation time. The required time for the passive mixing of a glycerol droplet pair was measured considering various thresholds for the final standard deviation of the gray intensity indices. This finding was of the order of magnitude of the diffusive mixing time scale and physically consistent with the Stokes flow regime.
The objective of the NSF RET (Research Experiences for Teachers) site program hosted by the University of Central Florida is to provide K-12 teachers with a hands-on engineering design experience covering all aspects of the Internet of Things, from the manufacturing of a sensor, to the hardware and software that allows it to connect to the Internet. This program gives teachers learning opportunities to explore the practical use of science for engineering applications, and provide a context in which students in their classroom can test their own scientific knowledge as they recognize the interplay among science, engineering and technology. The uniqueness of this site program lies in the engagement of teachers in various facets of scientific, engineering, and educational methods based on Train-the-Trainer model with rotation in multiple research labs. In order to support the STEM educational services for teachers and students in middle and high schools, our site program aims at creating competent teacher trainers who ensure quality pre-service and in-service teacher education, by providing multidisciplinary experiences that are relevant to the current technical development. Teachers in the adjacent public school districts are primary participants in this site program. Significant efforts have been made to recruit teachers serving underrepresented student populations, and female and minority teachers who can reach out to them. In our RET site program, the participants rotated to four different laboratories with a 1.5–3 week residency in each, where they learned about the practice of engineering in various disciplines at the research laboratories on the university campus under the guidance of faculty and graduate mentors. The teachers presented their learning outcomes in the final week and were invited back to share their educational implementation experiences in their classes. This site program provided teachers with interdisciplinary engineering design experiences relevant to innovative technical development, and helped them develop teacher-driven teaching modules that can be deployed in the classroom.
Taxis has been reported in many cells and microorganisms, due to their tendency to migrate toward favorable physical situations and avoid damage and death. Thermotaxis and chemotaxis are two of the major types of taxis that naturally occur on a daily basis. Understanding the details of the thermo- and chemotactic behavioral response of cells and microorganisms is necessary to reveal the body function, diagnosing diseases and developing therapeutic treatments. Considering the length-scale and range of effectiveness of these phenomena, advances in microfluidics have facilitated taxis experiments and enhanced the precision of controlling and capturing microscale samples. Microfabrication of fluidic chips could bridge the gap between in vitro and in situ biological assays, specifically in taxis experiments. Numerous efforts have been made to develop, fabricate and implement novel microchips to conduct taxis experiments and increase the accuracy of the results. The concepts originated from thermo- and chemotaxis, inspired novel ideas applicable to microfluidics as well, more specifically, thermocapillarity and chemocapillarity (or solutocapillarity) for the manipulation of single- and multi-phase fluid flows in microscale and fluidic control elements such as valves, pumps, mixers, traps, etc. This paper starts with a brief biological overview of the concept of thermo- and chemotaxis followed by the most recent developments in microchips used for thermo- and chemotaxis experiments. The last section of this review focuses on the microfluidic devices inspired by the concept of thermo- and chemotaxis. Various microfluidic devices that have either been used for, or inspired by thermo- and chemotaxis are reviewed categorically.
In this work, a central difference finite volume lattice Boltzmann method (CDFV-LBM) is developed to compute 2D inviscid compressible flows on triangular meshes. The numerical solution procedure adopted here for solving the lattice Boltzmann equation is nearly the same as the procedure used by Jameson et al. for the solution of the Euler equations. The integral form of the lattice Boltzmann equation using the Gauss divergence theorem is applied on a triangular cell and the numerical fluxes on each edge of the cell are set to the average of their values at the two adjacent cells. Appropriate numerical dissipation terms are added to the discretized lattice Boltzmann equation to have a stable solution. The Boltzmann equation is discretized in time using the fourth-order Runge-Kutta scheme. The computations are performed for three problems, namely, the isentropic vortex and the supersonic flow around a NACA0012 airfoil and over a circular-arc bump. The effect of changing the grid resolution and the dissipation coefficients on the accuracy of the results is also studied. Results obtained by applying the CDFV-LBM are compared with the available numerical results which show good agreement.
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