Introduction. It has been well established in the world that lipid disorders promote the development of atherosclerosis and its clinical consequences. This study aimed to assess the impacts of a Persian medicinal (PM) compound on lipid profile. Materials and Methods. From June 21 to October 21, 2020, a randomized double-blind controlled clinical trial was conducted with 74 dyslipidemic patients, who were randomly divided into two equally populated groups: one prescribed with a Persian medicinal herbal compound (n = 37) and a placebo group (n = 37). A Persian herbal medicine including fenugreek, sumac, and purslane is introduced. Biochemical parameters including 12-hour fasting serum levels of total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), very-low-density lipoprotein (VLDL), and triglyceride (TG) were measured before the initiation and after the completion of study protocol. Results. Percent changes of biochemical parameters include the following: intervention group = cholesterol: 35.22, Tg: 45.91, LDL: 24.81, HDL: 2.05, VLDL: 8.94 and placebo group = cholesterol: 6.94, Tg: −7.3, LDL: 7.37, HDL: 2.88, VLDL: −0.14. The serum levels of total cholesterol ( p = 0.01 ) and LDL ( p = 0.01 ) significantly decreased and no increase was recorded in HDL ( p = 0.03 ) levels over time in the intervention group. Furthermore, between-group analysis showed a statistically significant difference between the intervention and placebo groups in this regard. VLDL ( p = 0.2 ) and TG ( p = 0.2 ) levels also decreased, however not significantly. Conclusion. This study showed that a Persian medicinal herbal compound could be safe and beneficial to decrease the levels of serum cholesterol and LDL in dyslipidemic patients. However, larger long-term studies are recommended to clarify this effect.

In recent years, the common belief that herbal medications cause no side effects, have led to an increase in the consumption of these medications without prescription. Ginseng is one of the most commonly used herbs in the world and is a native of Eastern Asian countries such as China and Korea. It is also known to have several medicinal purposes. However, unreasonable use of this herb can bear consequences. In the current article, 28-year-old woman has consumed 4 capsules each day, which contained Ginseng roots, Alfalfa (Medicago sativa) extract, and Ziziphora (Ziziphora capitate) extract without a prescription to gain weight, which has resulted in serious side effects - including hepatotoxicity, psychologic, and gynecologic disorders. However, these symptoms were controlled with Chicory roots, Purslane and Jujube oxymel. PM focuses on the cooperation between food categories, nutritional instructions, food modulators, and medications. Regardless of their several therapeutic effects, medical herbs have been known to cause quite serious side effects if consumed unsystematically and without the surveillance of a doctor

Introduction: Nowadays, societies have witnessed a rapid increase of Fatty Liver, which is one of the most common liver diseases worldwide, due to some changes in lifestyle and the increased obesity and metabolic syndrome. Case presentation: in this study, the patient under research was a 41-year-old woman who was diagnosed with grade 3 fatty liver caused by the absence of a healthy diet and lifestyle. She was successfully treated using the methods of Traditional Iranian Medicine. Discussion: Classical medicine is not able to develop a certain treatment for this disease yet. Therefore, this article has mainly concentrated on the therapeutic effects of medicinal herbs on the liver. Conclusion: Delays in the diagnosis and treatment of fatty livermay lead to irreversibility or liver Cirrhosis, which cannot be treated using any method, but by liver transplants. However, the principles of PM (Persian Medicine) can be useful as useful in the prevention and treatment of this disease.

Objective: The first and most common cause of death in the world is due to cardiovascular diseases, and hyperlipidemia is one of the important and a critical controllable risk factors for these diseases. The connection between fat metabolism and a wide range of diseases, side effects of chemical drugs, and the increasing attention to the use of natural remedies reveal the necessity of further attention to the viewpoints of other schools of medicine, including complementary medicine. This review study aims to interpret hyperlipidemia from the perspective of Iranian Traditional Medicine (ITM). Methods: This is review study conducted based on a library method using the keywords related to hyperlipidemia to collect data through searching in online databases and ITM books. The data were analyzed based on the content analysis method. Results: Hyperlipidemia is mainly diagnosed by laboratory findings and often have no clear clinical symptoms. According to ITM, for diagnosing hyperlipidemia, attention should be paid to the role of liver, heart, and stomach along with the health principles and quadruple digestion. Conclusion: Hyperlipidemia is a condition that can be either pathological or physiological. According to ITM, it occurs due to the imbalance of humors inside the arteries and leads to higher blood concentration and. In some cases, it can be due to a disease and in some cases, it can be caused by the body’s compensatory response. Paying attention to the views of ITM can be effective in preventing disease and improving therapeutic interventions.