The recommended dosage of vismodegib is 150 mg/d until unendurable side effects develop or disease progression occurs.• The efficacy of vismodegib in the management of locally advanced basal cell carcinoma (BCC) and metastatic BCC is promising. Thus, it is now considered an effective substitute to surgical therapy.• Patients using vismodegib must be closely monitored, as it is commonly associated with adverse events.
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