This study aimed to determine the effectiveness of 5I's Learning Path with Cultural Approach embedded in Computer-Aided Instructional (CAI) Material to the conceptual understanding among 1 st year Bachelor of Science in Hospitality Management students, who are officially enrolled during 1 st Semester, School Year 2019-2020 taking Mathematics in the Modern World at Sultan Kudarat State University-Tacurong City Campus. Two sections of 31, students each class were used as participants of the study and randomly selected as control and experimental groups which employed a quasi-experimental research design. The level of conceptual understanding of the students was measured using their scores in taking the Conceptual Understanding Test (CUT). Mean, standard deviation, and the analysis of covariance (ANCOVA) were used to analyze the data collected. Results revealed that 5I's Learning Path with Cultural Approach embedded in CAI helped develop the students' conceptual understanding.