Although there are many more hurdles to be crossed in the field of adhesive dentistry, impressive progress has been achieved so far, and the vast amount of available research on the topic is an indicator of the importance of this matter and of the great efforts of researchers and dental material companies to reach a new level in the quality and longevity of resin-dentin bonds.

No abstract

This is an author version of the contribution published on:Questa è la versione dell 'autore dell'opera: J Eur Acad Dermatol Venereol. 2014 Apr;28(4):475-82. doi: 10.1111/jdv.12128 Design An 8-week randomized, double-blind controlled trial, followed by a six-month follow-up period.Setting Outpatients of the Oral Medicine Section, Lingotto Dental School, University of Turin, Italy.Patients Thirty patients were treated with either pimecrolimus 1% cream or tacrolimus 0.1% ointment, both mixed with an equivalent amount of 4% hydroxyethyl cellulose gel. InterventionThe medications were to be applied twice daily for 2 months as follow: finger rub application on dried lesions after meals without eating, drinking or speaking for at least half an hour afterwards. Each patient was examined at the beginning of therapy, and then every two weeks during the treatment and every 3 months of follow-up. Main Outcome Measures (i)To compare the effectiveness of topically applied pimecrolimus and tacrolimus; (ii) to evaluate which is more cost-effective; (iii) to determine which drug is faster in reducing signs and symptoms and (iv) which gives the longest remission.Results Both drugs were effective at inducing clinical improvement, with no statistical difference. Pimecrolimus creams revealed a significantly better stability of the therapeutic effectiveness (P=.031). ConclusionBoth medications would currently appear to be a treatment of choice for patients with unresponsive atrophic-erosive OLP. Pimecrolimus seemed to be more effective in providing long-term resolution of sings and symptoms. Future efforts are however needed to obtain more objective evidence of the benefit of these medications in the treatment of immunologically mediated oral mucosal lesion.

Objective:The aim of this in vitro study was to evaluate the marginal sealing ability of a bulk fill flowable resin composite on both enamel and dentin substrates.Materials and Methods:48 non-carious molars were selected and four Class-V cavities were prepared at the CEJ of each sample. Cavities were filled with Venus Diamond (Heraeus Kulzer); Venus Diamond Flow (Heraeus Kulzer) and Surefil SDR (Dentsply). Samples were divided into two groups: First group samples were immersed in a methylene blue solution for 30 min at 25°C. Second group samples were artificially aged and then treated with methylene blue. Samples were sectioned in the center of the restoration and observed with a 40x stereomicroscope, and the percentage of cavity infiltration was calculated.Results:Results were analyzed statistically by ANOVA (P < 0.05). The amount of infiltration was significantly lower for the enamel substrate compared with dentin (P = 0.0001) and in samples immediately immersed in methylene blue compared with those that were artificially aged (P = 0.011). The interaction between the composite material and the marginal substrate significantly affected dye penetration (P = 0.006).Conclusions:Bulk fill flowable resins provided significantly better marginal seal in dentin, both before and after artificial ageing. Nanohybrid resin composites and bulk fill flowable resins showed similar microleakage values at enamel margins. Bulk fills flowable resins provided significantly better marginal seal in dentin, both before and after artificial ageing. Nanohybrid resin composites and bulk fill flowable resins showed similar microleakage values at enamel margins.

No abstract