Background: Regular blood donation often cause iron deficiency. Changes of platelet count have been associated with iron deficiency anemia. We aimed to study the correlation between serum ferritin and platelet count in blood donors.Methods: Full blood count was measured by Sysmex-KX-21N Haematology Analyser. Serum ferritin was examined using electrochemiluminescence technology of Cobas e 411 Analyzer. Results:The only significant correlation between ferritin level and platelet count (r2 = 0.432, p = 0.012) demonstrated in blood donors whose serum ferritin was less than 60 ng/ mL. Conclusions:No significant association between ferritin and platelet count were found in healthy donors with ≥ or < 6 blood donations whereas the moderate positive association was found in blood donors with low ferritin concentration (< 60 ng/mL).