Estudio predictivo de los factores de riesgo perinatales relacionados con alteraciones en el neurodesarrollo Predictive study of perinatal risk factors related to neurodevelopmental disorders

The study of abdomen-wall malformations corresponds almost exclusively to omphalocele and gastroschisis, despite their different embryonic origin, studies of the associated risk factors should be performed. The objective of this study was to compare the perinatal risk factors that in uence mortality and birth-weight in patients with omphalocele and gastroschisis, using Bayesian analogues of the t-test, ANOVA, and logistic regression. The data were obtained from the Perinatal Computer System of the Hospital Gineco-Obstétrico Isidro Ayora. From January 2009 to December 2018, 68 patients with gastroschisis and 18 with omphalocele were found, with a rate of 7.7 and 2 per 10,000 live newborns. Patients with omphalocele had a better birth weight, gastroschisis, occurs in young mothers. In both conditions mortality is associated with low weight, malformations or comorbidities in the rst twelve days and respiratory and infectious complications after thirty days. The epidemiological pro le of patients with abdominal wall malformations does not show signi cant differences with what was reported in other populations.

No abstract

No abstract

Low birth weight is an important cause of morbidity and mortality in the neonatal and pediatric population. In addition to its relationship with adult non transmissible chronic diseases, due to its in uence on fetal metabolic programming. Considering the perinatal characteristics that in uence the weight of the newborn, the mother's age is a determining factor. The objective was to analyze the risk factors associated with low birth weight, in the different maternal age categories as a predictive factor. A 2009-2018 cross-sectional study was carried out, collecting data from 7069 neonates of the Hospital Gíneco-Obstétrico "Isidro Ayora", with birth weight between 500-2499gr. Multivariate predictive statistical models were applied according to the maternal age categories. It was found that the children of teenage mothers have the lowest affectation of birth weight, although they are a high-risk group, however, their biology and physiology are not affected by age and / or concurrent pathologies as occurs in the over 35 years old mothers. There are few national studies to compare these results, however, the validity of the nding is based on the number of cases studied and the period of time analyzed.