No author has a financial or proprietary interest in any material or method mentioned.

Aim To compare the development of posterior capsule opacification (PCO) between eyes with and without diabetes mellitus after single-piece hydrophobic acrylic intraocular lens implantation 4 years postoperatively. Methods In this prospective, observational case-control study carried out at Iladevi Cataract and IOL Research Centre, Ahmedabad, India, 75 consecutive eyes with diabetes mellitus (cases) were compared with 75 age-matched eyes with age-related cataract (controls). A detailed, preoperative and posterior segment evaluation was carried out in eyes with diabetes mellitus to detect the presence or absence of diabetic retinopathy (DR). The Mann-Whitney U-test was applied to compare the differences in the development of PCO between the two groups. Results There was no difference in median PCO between cases and controls at 1 month (2.0 vs 1.50, Po0.068), but cases had a higher median PCO at 12 months (2.95 vs 1.30, Po0.001). At 4 years, there was no significant difference in median PCO between cases and controls (3.75 vs 2.25, P ¼ 0.273). The duration of diabetes increased the incidence of PCO at 4 years (P ¼ 0.02). Severity of DR had no influence on the progress of PCO at 4 years (P ¼ 0.69). Conclusion Diabetes mellitus did not increase the incidence of PCO at 4 years. The duration of diabetes increased the risk of PCO. The severity of retinopathy did not influence the development of PCO.

The COBRA Polyzene-F stent met performance goals for TVF and LL at 9 months. There was an excellent safety profile, with infrequent late myocardial infarction and no stent thrombosis.

Axial myopia did not significantly increase the area or incidence of PCO at 4 years.

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