Background: Hypertension is a prevalent health problem in Saudi Arabia. It is a major risk factor of morbidity and mortality worldwide. Untreated hypertension can lead to serious and life threatening complications. Prevention of hypertension has a significant role in controlling the disease, which can be achieved by increasing the awareness in the community and changing their attitude and practices towards it. Aim:to assess knowledge, awareness and self-care practicesof hypertension among hypertensive patients. Methods: A cross-sectional study was conducted at the Out-Patient Department (OPD) of king Abdulaziz University hospital (KAUH) in Jeddah, Saudi Arabia. All confirmed cases of hypertension were interviewed using a pre-tested, semi-structured questionnaire. Results: The awareness level about hypertension was high in majority of cases (72.6%) and knowledge level was average in 54.7% of patients. While self-care practices level was below average 74.4% of participants. Awareness, Knowledge and self-management practices were found to be significantly poor among old age groups (above 50 years), males and less educated patients. Conclusion: Though there was adequate general knowledge and awareness on hypertension among hypertensive patients, but uncontrolled blood pressure (BP) and poor self-care practices were major findings among the studied population. There is a need to establish programs that increase community awareness regarding long term complications of uncontrolled hypertension and proper practices to control blood pressure so that it improves self-care practices and BP monitoring among hypertensive patients.