Background There are limited data on stable coronary artery disease (CAD) in the very elderly. The present study aimed to investigate incident cardiovascular events and mortality in older adults (≥85 years) included in a multicenter registry on stable CAD.Methods A long-term follow-up was performed in 198 patients ≥85 years with stable CAD, free from myocardial infarction (MI) or coronary revascularization within the year. The median age was 87 years. Clinical events during the follow-up period [death, MI, ischemic stroke, coronary revascularization and hospitalization for heart failure (HF)] were centrally adjudicated. ResultsThere were 164 deaths during follow-up. The cumulative risk of all-cause death was 9.1% at 1 year, 53.9% at 5 years and 85.5% at 10 years. The cause of death was adjudicated as cardiovascular in 64 patients with death from HF in 36 patients. Male gender, previous hospitalization for HF and an estimated glomerular filtration rate <60 ml/min/1.73 m 2 were independently associated with all-cause death. Ten-year cumulative incidences of MI, ischemic stroke and coronary revascularization were low (6.6, 7.7 and 6.6%, respectively). By contrast, the 10-year cumulative incidence of hospitalization for HF was high (27.8%). ConclusionThe 10-year mortality of elderly patients with stable CAD is very high. While ischemic events are relatively unfrequent, HF events are frequent and represent the most common cause of cardiovascular death in this population. Prevention and management of HF are important goals for physicians in charge of older adults with stable CAD.

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Malaria is a febrile and haemolyzing erythrocytopathy caused by the presence, development and multiplication of the Plasmodium genus protozoa in red blood cells, transmitted to humans by the bite of the female anopheles mosquito. It is a threat to travelers in general and in particular to military personnel from non-endemic countries and traveling to tropical regions.We tried to analyze the epidemiological, diagnostic, therapeutic and preventive characteristics of imported malaria, through a series of 81 cases of Moroccan soldiers who stayed in the Democratic Republic of Congo (DRC) and Ivory Cost (IC).The mean age was 33, 3 years, all male. 26 cases stayed in the DRC and 55 in the IC. We recorded one case of malaria in 2011, twentyseven cases in 2012, twelve in 2013, eighteen in 2014, and twenty three cases in 2015. The average time between the return from the endemic area and the onset of symptoms was 175 days. Fever was present in all cases and neurological disorders in one case. Plasmodium ovale was found in 55.5% of cases (n=45) followed by P. falcipaum in 39.5% (n=32). P. malariae was found in 3.4% of cases (n=3). The association P. falcipaum + P. ovale was observed only once (n=1). The average parasite rate was 0.69%, and it ranged from 0.01 to 8%. We regretted a single case of death due to P. ovale infection. Patients who were in the DRC used mefloquine in chemoprophylaxis, and those in IC used doxycycline until 2013, and then they converted to mefloquine.The Increase in the number of malaria cases imported from IC since 2012 appears to be due to the change of the place of deployment of half the Moroccan battalion deployed in the country. However, the increase in the number of cases from the DRC remains unexplained. Climatic factors or operational constraints could be the cause of their larger exposure to Anopheles risk.